Advanced Cardiac Imaging Techniques and Diagnostics

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Fezzi, S., Scheller, B., Cortese, B., Alfonso, F., Jeger, R., Colombo, A., Joner, M., Shin, E.-S., Kleber, F. X., Latib, A., Rissanen, T. T., Eccleshall, S., Ribichini, F., Tao, L., Koo, B.-K., Chieffo, A., Ge, J., Granada, J. F., Stoll, H.-P., … Serruys, P. W. (2025). Definitions and standardized endpoints for the use of drug-coated balloon in coronary artery disease: consensus document of the Drug Coated Balloon Academic Research Consortium. European Heart Journal. https://doi.org/10.1093/eurheartj/ehaf029
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Somsen, Y. B. O., de Winter, R. W., Wu, J., Hoek, R., Sprengers, R. W., Verouden, N. J., Claessen, B. E. P. M., Kleijn, S. A., Twisk, J. W. R., Henriques, J. P., Spratt, J. C., Rissanen, T. T., McEntegart, M. B., Maehara, A., Nap, A., & Knaapen, P. (2025). Design and rationale of the drug-coated balloon coronary angioplasty versus stenting for treatment of disease adjacent to a chronic total occlusion (Co-CTO) trial. American Heart Journal. https://doi.org/10.1016/j.ahj.2025.03.023
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Miller, R. JH., Bednarski, B., Cui, Y., Calsavara, V., Patel, K., Rozanski, A., Liang, J. X., Builoff, V., Acampa, W., Bateman, T. M., Di Carli, M., Dorbala, S., Einstein, A. J., Fish, M. B., Hauser, M. T., Kaufmann, P. A., Miller, E. J., Ruddy, T. D., Sharir, T., … Slomka, P. J. (2025). The Relationship Between Quantitative Ischemia, Early Revascularization, and Major Adverse Cardiovascular Events. JACC: Advances, 4(1), 101440. https://doi.org/10.1016/j.jacadv.2024.101440
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Kraal, A. Z., McFarlane, H. V., Pyne, J. D., Turney, I. C., Lao, P. J., Mazen, J., Brickman, A. M., & Manly, J. J. (2024). Does socioeconomic status modify the association between glycemic level and MRI markers of ADRD risk in middle‐aged adults? Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.092048
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Mares, J., Sharma, A., Guo, J., & Nuriel, T. (2024). Investigating the APOE4‐associated heterogeneity of imaging biomarkers across AD diagnostic stages. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.087489
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Tretter, J. T., Bedogni, F., Rodés-Cabau, J., Regueiro, A., Testa, L., Eleid, M. F., Chen, S., Galhardo, A., Ellenbogen, K. A., Leon, M. B., & Ben-Haim, S. (2024). Novel cardiac CT method for identifying the atrioventricular conduction axis by anatomic landmarks. Heart Rhythm. https://doi.org/10.1016/j.hrthm.2024.12.022
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Abdelfattah, O. M., Jacquemyn, X., Kapadia, S. R., Van Mieghem, N. M., Clavel, M.-A., Généreux, P., Leon, M., & Pibarot, P. (2024). Early Aortic Valve Replacement in Moderate Aortic Stenosis. JACC: Advances, 3(9), 101190. https://doi.org/10.1016/j.jacadv.2024.101190
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Torres, C., Lozier, M. R., Davidson, C. J., Ailawadi, G., Donatelle, M., Vedantam, K., Kodali, S. K., Leon, M. B., & Beohar, N. (2022). In-Hospital Outcomes of Transcatheter Tricuspid Valve Repair: An Analysis From the National Inpatient Sample. Journal of the Society for Cardiovascular Angiography & Interventions, 1(5), 100414. https://doi.org/10.1016/j.jscai.2022.100414
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Tian, L., Jaeger, B. C., Scialla, J. J., Budoff, M. J., Mehta, R. C., Jaar, B. G., Saab, G., Dobre, M. A., Reilly, M. P., Rader, D. J., Townsend, R. R., Lash, J. P., Greenland, P., Isakova, T., Bundy, J. D., Anderson, A. H., Appel, L. J., Chen, J., Cohen, D., … Unruh, M. L. (2024). Progression of Coronary Artery Calcification and Risk of Clinical Events in CKD: The Chronic Renal Insufficiency Cohort Study. American Journal of Kidney Diseases. https://doi.org/10.1053/j.ajkd.2024.06.018
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Shanbhag, A., Michalowska, A. N. N. A., Zhang, W. E. N. H. A. O., Miller, R. J. H., Lemley, M. A. R. K., Einstein, A. N. D. R. E. W., Liang, J. O. A. N. N. A., Builoff, V. A. L. E. R. I., Berman, D. A. N. I. E. L., Dey, D. A. M. I. N. I., & Slomka, P. I. O. T. R. (2024). Fully automated aortic diameter measurements on SPECT/CT attenuation maps in patients undergoing myocardial perfusion imaging. European Heart Journal - Cardiovascular Imaging, 25(Supplement_1). https://doi.org/10.1093/ehjci/jeae142.016
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Garnett, C., Sekerak, R., Fall, K., McEntegart, M., Moses, J. W., Leon, M. B., Kirtane, A. J., & Prasad, M. (2024). D-46 | IVUS-Guided Ultralow-Contrast PCI in Patients with CKD and Reduced Ejection Fraction: Safety Outcomes Analysis. Journal of the Society for Cardiovascular Angiography & Interventions, 3(5), 101740. https://doi.org/10.1016/j.jscai.2024.101740
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Adrichem, R., Hokken, T. W., Bouwmeester, S., Abdelkarim, O., Vogel, B., Blusztein, D. I., Veulemans, V., Kuneman, J. H., Geleijnse, M. L., Verhemel, S., Van den Dorpel, M. M. P., Kardys, I., Tonino, P. A. L., Chang, S. M., Faza, N. N., Jou, S., Ueyama, H. A., Bartkowiak, J., Zeus, T., … Van Mieghem, N. M. (2024). Diagnostic Value of Aortic Valve Calcification Levels in the Assessment of Low-Gradient Aortic Stenosis. JACC: Cardiovascular Imaging, 17(8), 847–860. https://doi.org/10.1016/j.jcmg.2024.03.014
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Garnett, C., Sekerak, R., Fall, K., McEntegart, M., Moses, J. W., Leon, M. B., Kirtane, A. J., & Prasad, M. (2024). OR5-2 | Radiation Exposure and Patient Outcomes in IVUS-Guided Near-Zero Contrast PCI versus IVUS-Guided Ultra-Low Contrast PCI. Journal of the Society for Cardiovascular Angiography & Interventions, 3(5), 101428. https://doi.org/10.1016/j.jscai.2024.101428
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Ezad, S. M., McEntegart, M., Dodd, M., Didagelos, M., Sidik, N., Li Kam Wa, M., Morgan, H. P., Pavlidis, A., Weerackody, R., Walsh, S. J., Spratt, J. C., Strange, J., Ludman, P., Chiribiri, A., Clayton, T., Petrie, M. C., O’Kane, P., Perera, D., Perera, D., … Bellamy, C. (2024). Impact of Anatomical and Viability-Guided Completeness of Revascularization on Clinical Outcomes in Ischemic Cardiomyopathy. Journal of the American College of Cardiology, 84(4), 340–350. https://doi.org/10.1016/j.jacc.2024.04.043
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Falah, B., Kotinkaduwa, L. N., Schonning, M. J., Redfors, B., de Waha, S., Granger, C. B., Maehara, A., Eitel, I., Thiele, H., & Stone, G. W. (2024). Microvascular Obstruction in Patients With Anterior STEMI Treated With Supersaturated Oxygen. Journal of the Society for Cardiovascular Angiography & Interventions, 3(5), 101356. https://doi.org/10.1016/j.jscai.2024.101356
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Shah, S. M., Tremmel, J. A., Henry, T. D., Smilowitz, N. R., Prasad, M., Kobayashi, Y., Henry, G. A., Samady, H., Samuels, B. A., Lerman, A., Moses, J. W., Pietras, C., Zhang, Z., Tirziu, D., Parise, H., Cristea, E., Chamié, D., Grubman, D., Henrici, K., … Lansky, A. J. (2024). Determining the Cause of Coronary Vasomotor Disorders in Patients With Ischemia and Nonobstructive Coronary Arteries: Design and Rationale of the DISCOVER INOCA Prospective, Multicenter Registry. Journal of the Society for Cardiovascular Angiography & Interventions, 3(6), 102046. https://doi.org/10.1016/j.jscai.2024.102046
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Medranda, G. A., Faraz, H. A., Thompson, J. B., Zhang, Y., Bharadwaj, A. S., Osborn, E. A., Abu-Much, A., Lansky, A. J., Basir, M. B., Moses, J. W., O’Neill, W. W., Grines, C. L., & Baron, S. J. (2024). Association of Preprocedural SYNTAX Score With Outcomes in Impella-Assisted High-Risk Percutaneous Coronary Intervention. Journal of the Society for Cardiovascular Angiography & Interventions, 101981. https://doi.org/10.1016/j.jscai.2024.101981
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Bhave, S., Rodriguez, V., Poterucha, T., Mutasa, S., Aberle, D., Capaccione, K. M., Chen, Y., Dsouza, B., Dumeer, S., Goldstein, J., Hodes, A., Leb, J., Lungren, M., Miller, M., Monoky, D., Navot, B., Wattamwar, K., Wattamwar, A., Clerkin, K., … Elias, P. (2024). Deep learning to detect left ventricular structural abnormalities in chest X-rays. European Heart Journal, 45(22), 2002–2012. https://doi.org/10.1093/eurheartj/ehad782
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Kapadia, S. R., Krishnaswamy, A., Whisenant, B., Potluri, S., Iyer, V., Aragon, J., Gideon, P., Strote, J., Leonardi, R., Agarwal, H., Larrain, G., Sanchez, C., Panaich, S. S., Harvey, J., Vahl, T., Menon, V., Wolski, K., Wang, Q., & Leon, M. B. (2024). Concomitant Left Atrial Appendage Occlusion and Transcatheter Aortic Valve Replacement Among Patients With Atrial Fibrillation. Circulation, 149(10), 734–743. https://doi.org/10.1161/circulationaha.123.067312
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Sidik, N. P., Stanley, B., Sykes, R., Morrow, A. J., Bradley, C. P., McDermott, M., Ford, T. J., Roditi, G., Hargreaves, A., Stobo, D., Adams, J., Byrne, J., Mahrous, A., Young, R., Carrick, D., McGeoch, R., Corcoran, D., Lang, N. N., Heggie, R., … Berry, C. (2024). Invasive Endotyping in Patients With Angina and No Obstructive Coronary Artery Disease: A Randomized Controlled Trial. Circulation, 149(1), 7–23. https://doi.org/10.1161/circulationaha.123.064751
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El-Zein, R. S., Malik, A. O., Cohen, D. J., Spertus, J. A., Saxon, J. T., Pibarot, P., Hahn, R. T., Alu, M. C., Shang, K., Kodali, S. K., Thourani, V. H., Leon, M. B., Mack, M. J., & Chhatriwalla, A. K. (2024). Diastolic Dysfunction and Health Status Outcomes After Transcatheter Aortic Valve Replacement. Structural Heart, 8(1), 100225. https://doi.org/10.1016/j.shj.2023.100225
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Ouyang, D., Theurer, J., Stein, N. R., Hughes, J. W., Elias, P., He, B., Yuan, N., Duffy, G., Sandhu, R. K., Ebinger, J., Botting, P., Jujjavarapu, M., Claggett, B., Tooley, J. E., Poterucha, T., Chen, J. H., Nurok, M., Perez, M., Perotte, A., … Albert, C. M. (2024). Electrocardiographic deep learning for predicting post-procedural mortality: a model development and validation study. The Lancet Digital Health, 6(1), e70–e78. https://doi.org/10.1016/s2589-7500(23)00220-0
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Abu-Much, A., Grines, C. L., Batchelor, W. B., Maini, A. S., Zhang, Y., Redfors, B., Bellumkonda, L., Bharadwaj, A. S., Moses, J. W., Truesdell, A. G., Li, Y., Baron, S. J., Lansky, A. J., Basir, M. B., Cohen, D. J., & O’Neill, W. W. (2024). Influence of left ventricular ejection fraction in patients undergoing contemporary pLVAD-supported high-risk PCI. American Heart Journal, 269, 139–148. https://doi.org/10.1016/j.ahj.2023.12.015
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Kodali, S., Hahn, R. T., Makkar, R., Makar, M., Davidson, C. J., Puthumana, J. J., Zahr, F., Chadderdon, S., Fam, N., Ong, G., Yadav, P., Thourani, V., Vannan, M. A., O’Neill, W. W., Wang, D. D., Tchétché, D., Dumonteil, N., Bonfils, L., … Lepage, L. (2023). Transfemoral tricuspid valve replacement and one-year outcomes: the TRISCEND study. European Heart Journal, 44(46), 4862–4873. https://doi.org/10.1093/eurheartj/ehad667
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Hughes, J. W., Tooley, J., Torres Soto, J., Ostropolets, A., Poterucha, T., Christensen, M. K., Yuan, N., Ehlert, B., Kaur, D., Kang, G., Rogers, A., Narayan, S., Elias, P., Ouyang, D., Ashley, E., Zou, J., & Perez, M. V. (2023). A deep learning-based electrocardiogram risk score for long term cardiovascular death and disease. Npj Digital Medicine, 6(1). https://doi.org/10.1038/s41746-023-00916-6
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Dimagli, A., Spadaccio, C., Myers, A., Demetres, M., Rademaker‐Havinga, T., Stone, G. W., Spertus, J. A., Redfors, B., Fremes, S., Gaudino, M., & Masterson Creber, R. (2023). Quality of Life After Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting. Journal of the American Heart Association, 12(22). https://doi.org/10.1161/jaha.123.030069
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Gadde, K. M., Yin, X., Goldberg, R. B., Orchard, T. J., Schlögl, M., Dabelea, D., Ibebuogu, U. N., Watson, K. E., Pi‐Sunyer, F. X., Crandall, J. P., Temprosa, M., & Luchsinger, J. A. (2023). Coronary Artery Calcium and Cognitive Decline in the Diabetes Prevention Program Outcomes Study. Journal of the American Heart Association, 12(21). https://doi.org/10.1161/jaha.123.029671
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Adrichem, R., Bouwmeester, S., Abdelkarim, O., Vogel, B., Blusztein, D. I., Veulemans, V., Kuneman, J. H., Geleijnse, M., Bax, J. J., Bertrand, P. B., Kodali, S. K., Mehran, R., Little, S. H., Houthuizen, P., & Van Mieghem, N. M. (2023). Dobutamine stress echocardiography remains indispensable for the diagnosis of low-flow low-gradient severe aortic stenosis. European Heart Journal, 44(Supplement_2). https://doi.org/10.1093/eurheartj/ehad655.1654
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Zahr, F., Song, H. K., Chadderdon, S., Gada, H., Mumtaz, M., Byrne, T., Kirshner, M., Sharma, S., Kodali, S., George, I., Merhi, W., Yarboro, L., Sorajja, P., Bapat, V., Bajwa, T., Weiss, E., Thaden, J. J., Gearhart, E., Lim, S., … Leon, M. B. (2023). 1-Year Outcomes Following Transfemoral Transseptal Transcatheter Mitral Valve Replacement. JACC: Cardiovascular Interventions, 16(23), 2868–2879. https://doi.org/10.1016/j.jcin.2023.10.001
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Kar, S., Doshi, S. K., Alkhouli, M., Camm, A. J., Coylewright, M., Gibson, M. C., Granger, C. B., Gurol, M. E., Huber, K., Mansour, M., Nair, D. G., Natale, A., Pocock, S. J., Reddy, V. R., Saliba, W., Christen, T., Allocco, D. J., Ellenbogen, K. A., & Leon, M. B. (2023). Rationale and design of a randomized study comparing the Watchman FLX device to DOACs in patients with atrial fibrillation. American Heart Journal, 264, 123–132. https://doi.org/10.1016/j.ahj.2023.05.022
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Bartkowiak, J., Vivekanantham, H., Kassar, M., Dernektsi, C., Agarwal, V., Lebehn, M., Windecker, S., Brugger, N., Hahn, R., & Praz, F. (2023). TCT-500 Computed Tomography Anatomic Predictors of Procedural Success in Patients Undergoing Tricuspid Transcatheter Edge-to-Edge Repair. Journal of the American College of Cardiology, 82(17), B201. https://doi.org/10.1016/j.jacc.2023.09.509
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Karacsonyi, J., Stanberry, L., Bergstedt, S., Rempakos, A., Kostantinis, S., Simsek, B., Alexandrou, M., Allana, S., Al-Ogaili, A., Alaswad, K., Krestyaninov, O., Karmpaliotis, D., Kirtane, A., McEntegart, M., Khatri, J., Jaffer, F., Poommipanit, P., Choi, J., Gorgulu, S., … Brilakis, E. (2023). TCT-607 Machine Learning for Predicting Major Adverse Cardiac Events in Percutaneous Coronary Intervention of Coronary Artery Chronic Total Occlusion. Journal of the American College of Cardiology, 82(17), B244. https://doi.org/10.1016/j.jacc.2023.09.618
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Sekerak, R., Garnett, C., Ben-Ami, J., Madhavan, M., Kirtane, A., McEntegart, M., Fall, K., Maehara, A., Moses, J., Leon, M., & Prasad, M. (2023). TCT-505 CKD Risk Stratification Within a Cohort of Patients Undergoing Ultralow-Contrast IVUS-Guided PCI. Journal of the American College of Cardiology, 82(17), B203–B204. https://doi.org/10.1016/j.jacc.2023.09.515
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Husain-Syed, F., DiFrancesco, M. F., Deo, R., Barr, R. G., Scialla, J. J., Bluemke, D. A., Kronmal, R. A., Lima, J. A. C., Praestgaard, A., Tracy, R. P., Shlipak, M., Kawut, S. M., & Kim, J. S. (2023). Associations between eGFR and albuminuria with right ventricular measures: the MESA-Right Ventricle study. Clinical Kidney Journal, 16(9), 1508–1520. https://doi.org/10.1093/ckj/sfad096
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Prasad, M., Ahmad, Y., Howard, J. P., Ben-Ami, J., Madhavan, M. V., Kirtane, A. J., McEntegart, M., Flattery, E., Stone, G. W., Leon, M. B., & Moses, J. W. (2023). Long-term Incidence of Myocardial Infarction and Death After CABG and PCI for Isolated Left Anterior Descending Artery Disease: A Meta-analysis of Randomized Controlled Trials. Journal of the Society for Cardiovascular Angiography & Interventions, 2(4), 100636. https://doi.org/10.1016/j.jscai.2023.100636
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Stone, G. W., Kereiakes, D. J., Gori, T., Metzger, D. C., Stein, B., Erickson, M., Torzewski, J., Kabour, A., Piegari, G., Cavendish, J., Bertolet, B., Stockelman, K. A., West, N. E. J., Ben-Yehuda, O., Choi, J. W., Marx, S. O., Spertus, J. A., & Ellis, S. G. (2023). 5-Year Outcomes After Bioresorbable Coronary Scaffolds Implanted With Improved Technique. Journal of the American College of Cardiology, 82(3), 183–195. https://doi.org/10.1016/j.jacc.2023.05.003
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Baker, S. D., Bates, S. E., Brooks, G. A., Dahut, W. L., Diasio, R. B., El-Deiry, W. S., Evans, W. E., Figg, W. D., Hertz, D. L., Hicks, J. K., Kamath, S., Kasi, P. M., Knepper, T. C., McLeod, H. L., O’Donnell, P. H., Relling, M. V., Rudek, M. A., Sissung, T. M., Smith, D. M., … Walko, C. M. (2023). DPYD Testing: Time to Put Patient Safety First. Journal of Clinical Oncology, 41(15), 2701–2705. https://doi.org/10.1200/jco.22.02364
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Hussain, Y., Saito, S., Curtis, M., Kereiakes, D. J., Baumbach, A., Zidar, J. P., McLaurin, B., Dib, N., Smits, P. C., Jiménez Díaz, V. A., Cequier, Á., Hofma, S. H., Pietras, C., Dressler, O., Issever, M. O., Windecker, S., Leon, M. B., & Lansky, A. J. (2023). The Supreme Biodegradable Polymer DES in Acute and Chronic Coronary Syndromes: A PIONEER III Substudy. Journal of the Society for Cardiovascular Angiography & Interventions, 2(3), 100629. https://doi.org/10.1016/j.jscai.2023.100629
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Messenger, J. C., Strobel, A. L., Danenberg, H., De Vroey, F., Kirtane, A. J., Parikh, M. A., Karmpaliotis, D., Hennessey, B., Curcio, A., van Mourik, M., Eshuis, P., & Escaned, J. (2023). LB-1 | Real-World Evaluation of the Feasibility and Quality of PCI Guidance Using Dynamic Coronary Roadmap: A Secondary Analysis of the DCR4Contrast Multicenter, International Randomized Control Trial. Journal of the Society for Cardiovascular Angiography & Interventions, 2(3), 100638. https://doi.org/10.1016/j.jscai.2023.100638
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Gogia, S., Vahl, T. P., Thourani, V. H., Yadav, P. K., George, I., Kodali, S. K., Hamid, N., Ranard, L., Chen, T., Matsumura, M., Maehara, A., Treede, H., Baldus, S., Daniels, D., Sheridan, B. C., Zahr, F., Russo, M. J., McCabe, J. M., Chetcuti, S. J., … Khalique, O. K. (2023). Cardiac Computed Tomography Angiography Anatomical Characterization of Patients Screened for a Dedicated Transfemoral Transcatheter Valve System for Primary Aortic Regurgitation. Structural Heart, 7(3), 100164. https://doi.org/10.1016/j.shj.2023.100164
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Zeijlon, R., Jha, S., Le, V., Chamat, J., Shekka Espinosa, A., Poller, A., Thorleifsson, S., Bobbio, E., Mellberg, T., Pirazzi, C., Gudmundsson, T., Martinsson, A., Angerås, O., Råmunddal, T., Omerovic, E., & Redfors, B. (2023). Temporal electrocardiographic changes in anterior ST elevation myocardial infarction versus the Takotsubo syndrome. IJC Heart & Vasculature, 45, 101187. https://doi.org/10.1016/j.ijcha.2023.101187
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