Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma and identifies matrix-activated therapeutic targets

Cruz-Acuña, R., Kariuki, S. W., Sugiura, K., Karaiskos, S., Plaster, E. M., Loebel, C., Efe, G., Karakasheva, T., Gabre, J. T., Hu, J., Burdick, J. A., & Rustgi, A. K. (2023). Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma and identifies matrix-activated therapeutic targets. Journal of Clinical Investigation, 133(23). https://doi.org/10.1172/jci168146
Authors:
Ricardo Cruz‐Acuña
Secunda W. Kariuki
Katsura Sugiura
Spyros Karaiskos
Eleanor M. Plaster
Claudia Loebel
Gizem Efe
Tatiana A. Karakasheva
Joel Gabre
Jianhua Hu
Jason A. Burdick
Anil K. Rustgi
Affiliated Authors:
Ricardo Cruz‐Acuña
Secunda W. Kariuki
Katsura Sugiura
Spyros Karaiskos
Gizem Efe
Joel Gabre
Jianhua Hu
Anil K. Rustgi
Columbia Affiliation:
Subjects:
Adenocarcinoma (MeSH)
Esophageal Neoplasms (MeSH)
Cell Mechanics and Extracellular Matrix Interactions (OpenAlex Topic)
Cancer Stem Cells and Tumor Metastasis (OpenAlex Topic)
Tissue Engineering and Regenerative Medicine (OpenAlex Topic)
Author Keywords:
cancer
cell biology
drug therapy
extracellular matrix
oncology
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Publication Type:
Article
Unique ID:
10.1172/jci168146
PMID:
37788109
DOI:
10.1172/jci168146
Journal:
Journal of Clinical Investigation
Publication Date:
Data Source:
OpenAlex
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