Chimeric Antigen Receptor T Cell with an Inducible Caspase-9 Suicide Gene Eradicates Uveal Melanoma Liver Metastases via B7-H3 Targeting

Ventin, M., Cattaneo, G., Arya, S., Jia, J., Gelmi, M. C., Sun, Y., Maggs, L., Ksander, B. R., Verdijk, R. M., Boland, G. M., Jenkins, R. W., Haq, R., Jager, M. J., Wang, X., Ryeom, S., & Ferrone, C. R. (2024). Chimeric Antigen Receptor T Cell with an Inducible Caspase-9 Suicide Gene Eradicates Uveal Melanoma Liver Metastases via B7-H3 Targeting. Clinical Cancer Research, 30(15), 3243–3258. https://doi.org/10.1158/1078-0432.ccr-24-0071
Authors:
Marco Ventin
Giulia Cattaneo
Shahrzad Arya
Jingyu Jia
Maria C Gelmi
Yi Sun
Luke Maggs
Bruce R Ksander
Robert M Verdijk
Genevieve M Boland
Russell W Jenkins
Rizwan Haq
Martine J Jager
Xinhui Wang
Sandra Ryeom
Cristina R Ferrone
Affiliated Authors:
Sandra Ryeom
Columbia Affiliation:
Subjects:
Uveal Neoplasms (MeSH)
B7 Antigens (MeSH)
Melanoma (MeSH)
Liver Neoplasms (MeSH)
Receptors, Chimeric Antigen (MeSH)
Caspase 9 (MeSH)
Genes, Transgenic, Suicide (MeSH)
Xenograft Model Antitumor Assays (MeSH)
Immunotherapy, Adoptive (MeSH)
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Publication Type:
Article
Unique ID:
10.1158/1078-0432.ccr-24-0071
PMID:
38767611
DOI:
10.1158/1078-0432.ccr-24-0071
Journal:
Clinical Cancer Research
Publication Date:
Data Source:
PubMed
Source Link:
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