Therapeutic targeting of the NOTCH1 and neddylation pathways in T cell acute lymphoblastic leukemia

Bertulfo, K., Perez-Duran, P., Miller, H., Ma, C., Ambesi-Impiombato, A., Samon, J., Mackey, A., Lin, W.-H. W., Ferrando, A. A., & Palomero, T. (2025). Therapeutic targeting of the NOTCH1 and neddylation pathways in T cell acute lymphoblastic leukemia. Proceedings of the National Academy of Sciences, 122(14). https://doi.org/10.1073/pnas.2426742122
Authors:
Kalay Bertulfo
Pablo Perez-Duran
Hannah Miller
Cindy Ma
Alberto Ambesi-Impiombato
Jeremy Samon
Adam Mackey
Wen-Hsuan Wendy Lin
Adolfo A Ferrando
Teresa Palomero
Affiliated Authors:
Kalay Bertulfo
Pablo Perez-Duran
Hannah Miller
Cindy Ma
Alberto Ambesi-Impiombato
Jeremy Samon
Adam Mackey
Wen-Hsuan Wendy Lin
Adolfo A Ferrando
Teresa Palomero
Columbia Affiliation:
Subjects:
Epidemiology and Treatment of Childhood Leukemia (OpenAlex Topic)
Acute Myeloid Leukemia (OpenAlex Topic)
Molecular Mechanisms of Kidney Development and Disease (OpenAlex Topic)
Receptor, Notch1 (MeSH)
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (MeSH)
Pyrimidines (MeSH)
Cyclopentanes (MeSH)
Signal Transduction (MeSH)
Author Keywords:
hes1
notch1
t cell lymphoblastic leukemia (t-all)
experimental therapeutics
neddylation
elink
Publication Type:
Article
Unique ID:
10.1073/pnas.2426742122
PMID:
40163723
DOI:
10.1073/pnas.2426742122
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View OpenAlex Record

Record Created: