Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining

Godinez-Macias, K. P., Chen, D., Wallis, J. L., Siegel, M. G., Adam, A., Bopp, S., Carolino, K., Coulson, L. B., Durst, G., Thathy, V., Esherick, L., Farringer, M. A., Flannery, E. L., Forte, B., Liu, T., Godoy Magalhaes, L., Gupta, A. K., Istvan, E. S., Jiang, T., … Winzeler, E. A. (2025). Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining. Npj Drug Discovery, 2(1). https://doi.org/10.1038/s44386-025-00006-5
Authors:
Karla P Godinez-Macias
Daisy Chen
J Lincoln Wallis
Miles G Siegel
Anna Adam
Selina Bopp
Krypton Carolino
Lauren B Coulson
Greg Durst
Vandana Thathy
Lisl Esherick
Madeline A Farringer
Erika L Flannery
Barbara Forte
Tiqing Liu
Luma Godoy Magalhaes
Anil K Gupta
Eva S Istvan
Tiantian Jiang
Krittikorn Kumpornsin
Karen Lobb
Kyle J McLean
Igor M R Moura
John Okombo
N Connor Payne
Andrew Plater
Srinivasa P S Rao
Jair L Siqueira-Neto
Bente A Somsen
Robert L Summers
Rumin Zhang
Michael K Gilson
Francisco-Javier Gamo
Brice Campo
Beatriz Baragaña
James Duffy
Ian H Gilbert
Amanda K Lukens
Koen J Dechering
Jacquin C Niles
Case W McNamara
Xiu Cheng
Lyn-Marie Birkholtz
Alfred W Bronkhorst
David A Fidock
Dyann F Wirth
Daniel E Goldberg
Marcus C S Lee
Elizabeth A Winzeler
Affiliated Authors:
Vandana Thathy
Igor M R Moura
John Okombo
David A Fidock
Columbia Affiliation:
Subjects:
Prediction of Peptide-MHC Binding Affinity (OpenAlex Topic)
Malaria (OpenAlex Topic)
Hepatitis C Infection and Treatment (OpenAlex Topic)
Author Keywords:
target identification
target validation
elink
Publication Type:
Article
Unique ID:
10.1038/s44386-025-00006-5
PMID:
40066064
DOI:
10.1038/s44386-025-00006-5
Journal:
NPJ Drug Discovery
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View OpenAlex Record

Record Created: