Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia

Llibre-Guerra, J. J., Fernandez, M. V., Joseph-Mathurin, N., Bian, S., Carter, K., Li, Y., Aschenbrenner, A. J., Pottier, C., Sigurdson, W., McDade, E., Gordon, B. A., Renton, A. E., Benzinger, T. L. S., Ibañez, L., Barthelemy, N., Johnson, M., Hassenstab, J., Wang, G., Goate, A. M., … Ziegemeier, E. (2025). Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia. Nature Medicine, 31(4), 1267–1275. https://doi.org/10.1038/s41591-025-03494-0
Authors:
Jorge J. Llibre-Guerra
M. Victoria Fernandez
Nelly Joseph-Mathurin
Shijia Bian
Kathleen Carter
Yan Li
Andrew J. Aschenbrenner
Cyril Pottier
Wendy Sigurdson
Eric McDade
Brian A. Gordon
Alan E. Renton
Tammie L. S. Benzinger
Laura Ibañez
Nico Barthelemy
Matthew Johnson
Jason Hassenstab
Guoqiao Wang
Alison M. Goate
Dan Western
Ciyang Wang
Diana Hobbs
Alisha Daniels
Celeste Karch
John C. Morris
Carlos Cruchaga
Erik C. B. Johnson
Randall J. Bateman
Ellen Ziegemeier
Angela Ziegemeier
Jinbin Xu
Xiong Xu
Chengjie Xiong
Yong Wang
Qing Wang
Jonathan Vöglein
Andrei Vlassenko
Silvia Vazquez
Reda Timofejavaite
Ezequiel Surace
Charlene Supnet-Bell
Sarah Stout
Jennifer Stauber
Jennifer Smith
Karina Skrbec
Ashlee Simmons
Nicholas T. Seyfried
Laura Serna
Michio Senda
Jalen Scott
Peter R. Schofield
Raquel Sanchez-Valle
Stephen Salloway
Edita Sabaredzovic
Natalie S. Ryan
Pedro Rosa-Neto
Jee Hoon Roh
Yvonne Rödenbeck
Jacqueline Rizzo
John Ringman
Gerald Reischl
Laura Ramirez
Christine Pulizos
Danielle M. Picarello
Richard J. Perrin
Ulrike Obermueller
James M. Noble
Yoshiki Niimi
Yuzheng Nie
Joyce Nicklaus
Hiroshi Mori
Matthew Minton
Nicole McKay
Austin McCullough
Colin Masters
Parinaz Massoumzadeh
Ralph Martins
Mariana Martin
Jacob Marsh
Courtney Maa
Ruijin Lu
Francisco Lopera
Yudy Milena Leon
Johannes Levin
Allan I. Levey
Jae-Hong Lee
Christoph Laske
Christian la Fougère
Elke Kuder-Buletta
Deborah Koudelis
Sarah Keefe
Kensaku Kasuga
Mathias Jucker
Gina Jerome
Kelley Jackson
Kenji Ishii
Takanobu Ishiguro
Snezana Ikonomovic
Takeshi Ikeuchi
Edward D. Huey
Russ Hornbeck
David M. Holtzman
Cortaiga Hellm
Emily Gremminger
Neill R. Graff-Radford
Susanne Graber-Sultan
Manu Goyal
Brian Fulton-Howard
Erin Franklin
Nick C. Fox
Shaney Flores
Martin Farlow
Anne M. Fagan
Emma Devenney
Gregory S. Day
Laura Courtney
Patricio Chrem Mendez
Jasmeer P. Chhatwal
Charles Chen
Allison Chen
David M. Cash
William S. Brooks
Yamile Bocanegra
Sarah B. Berman
Jacob A. Bechara
Jamie Bartzel
Jessica Banks
Bryce Baker
Ana Baena
Ricardo F. Allegri
David Aguillon
Affiliated Authors:
James M. Noble
Columbia Affiliation:
elink
Publication Type:
Article
Unique ID:
10.1038/s41591-025-03494-0
PMID:
39930140
DOI:
10.1038/s41591-025-03494-0
Journal:
Nature Medicine
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record

Record Created: