Understanding therapeutic tolerance through a mathematical model of drug-induced resistance

Gevertz, J. L., Greene, J. M., Prosperi, S., Comandante-Lou, N., & Sontag, E. D. (2025). Understanding therapeutic tolerance through a mathematical model of drug-induced resistance. Npj Systems Biology and Applications, 11(1). https://doi.org/10.1038/s41540-025-00511-3
Authors:
Jana L Gevertz
James M Greene
Samantha Prosperi
Natacha Comandante-Lou
Eduardo D Sontag
Affiliated Authors:
Natacha Comandante-Lou
Columbia Affiliation:
Subjects:
Computational Methods in Drug Discovery (OpenAlex Topic)
Drug Metabolism and Pharmacogenomics (OpenAlex Topic)
Mathematical Modeling of Cancer Growth and Treatment (OpenAlex Topic)
Drug Resistance, Neoplasm (MeSH)
Models, Biological (MeSH)
Neoplasms (MeSH)
Antineoplastic Agents (MeSH)
Drug Tolerance (MeSH)
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Publication Type:
Article
Unique ID:
10.1038/s41540-025-00511-3
PMID:
40204801
DOI:
10.1038/s41540-025-00511-3
Journal:
npj Systems Biology and Applications
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created: