Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability

Gorman, J., Cheung, C. S.-F., Duan, Z., Ou, L., Wang, M., Chen, X., Cheng, C., Biju, A., Sun, Y., Wang, P., Yang, Y., Zhang, B., Boyington, J. C., Bylund, T., Charaf, S., Chen, S. J., Du, H., Henry, A. R., Liu, T., … Kwong, P. D. (2024). Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability. Nature Communications, 15(1). https://doi.org/10.1038/s41467-023-44534-y
Authors:
Jason Gorman
Crystal Sao-Fong Cheung
Zhijian Duan
Li Ou
Maple Wang
Xuejun Chen
Cheng Cheng
Andrea Biju
Yaping Sun
Pengfei Wang
Yongping Yang
Baoshan Zhang
Jeffrey C Boyington
Tatsiana Bylund
Sam Charaf
Steven J Chen
Haijuan Du
Amy R Henry
Tracy Liu
Edward K Sarfo
Chaim A Schramm
Chen-Hsiang Shen
Tyler Stephens
I-Ting Teng
John-Paul Todd
Yaroslav Tsybovsky
Raffaello Verardi
Danyi Wang
Shuishu Wang
Zhantong Wang
Cheng-Yan Zheng
Tongqing Zhou
Daniel C Douek
John R Mascola
David D Ho
Mitchell Ho
Peter D Kwong
Affiliated Authors:
Maple Wang
Pengfei Wang
David D Ho
Columbia Affiliation:
Subjects:
Single-Domain Antibodies (MeSH)
Lassa Fever (MeSH)
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Publication Type:
Article
Unique ID:
10.1038/s41467-023-44534-y
PMID:
38177144
DOI:
10.1038/s41467-023-44534-y
Journal:
Nature Communications
Publication Date:
Data Source:
PubMed
Source Link:
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