Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases

Wang, L., Bohmer, M. J., Wang, J., Nardella, F., Calla, J., Laureano De Souza, M., Schindler, K. A., Montejo, L., Mittal, N., Rocamora, F., Treat, M., Charlton, J. T., Tumwebaze, P. K., Rosenthal, P. J., Cooper, R. A., Chakrabarti, R., Winzeler, E. A., Chakrabarti, D., & Gray, N. S. (2024). Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. Journal of Medicinal Chemistry, 67(2), 1460–1480. https://doi.org/10.1021/acs.jmedchem.3c02046
Authors:
Lushun Wang
Monica J Bohmer
Jinhua Wang
Flore Nardella
Jaeson Calla
Mariana Laureano De Souza
Kyra A Schindler
Lukas Montejo
Nimisha Mittal
Frances Rocamora
Mayland Treat
Jordan T Charlton
Patrick K Tumwebaze
Philip J Rosenthal
Roland A Cooper
Ratna Chakrabarti
Elizabeth A Winzeler
Debopam Chakrabarti
Nathanael S Gray
Affiliated Authors:
Kyra A Schindler
Subjects:
Antimalarials (MeSH)
Malaria (MeSH)
Publication Type:
Article
Unique ID:
10.1021/acs.jmedchem.3c02046
PMID:
Publication Date:
Data Source:
PubMed

Record Created: