Loss of FXR or Bile Acid-dependent Inhibition accelerate carcinogenesis of Gastroesophageal Adenocarcinoma

Baumeister, T., Proaño-Vasco, A., Metwaly, A., Kleigrewe, K., Kuznetsov, A., Schömig, L., Borgmann, M., Khiat, M., Anand, A., Strangmann, J., Böttcher, K., Haller, D., Dunkel, A., Somoza, V., Reiter, S., Meng, C., Thimme, R., Schmid, R. M., Patil, D. T., … Quante, M. (2025). Loss of FXR or Bile Acid-dependent Inhibition accelerate carcinogenesis of Gastroesophageal Adenocarcinoma. Cellular and Molecular Gastroenterology and Hepatology, 101505. https://doi.org/10.1016/j.jcmgh.2025.101505
Authors:
Theresa Baumeister
Andrea Proaño-Vasco
Amira Metwaly
Karin Kleigrewe
Alexander Kuznetsov
Linus Schömig
Martin Borgmann
Mohammed Khiat
Akanksha Anand
Julia Strangmann
Katrin Böttcher
Dirk Haller
Andreas Dunkel
Veronika Somoza
Sinah Reiter
Chen Meng
Robert Thimme
Roland M Schmid
Deepa T Patil
Elke Burgermeister
Yiming Huang
Yiwei Sun
Harris H Wang
Timothy C Wang
Julian A Abrams
Michael Quante
Affiliated Authors:
Yiming Huang
Yiwei Sun
Harris H Wang
Timothy C Wang
Julian A Abrams
Author Keywords:
barrett esophagus (be)
gastroesophageal adenocarcinoma (geac)
bile acids (ba)
farnesoid x receptor (fxr)
obeticholic acid (oca)
Publication Type:
Article
Unique ID:
10.1016/j.jcmgh.2025.101505
PMID:
Journal:
Publication Date:
Data Source:
PubMed

Record Created: