Elevated expression of the retrotransposon LINE-1 drives Alzheimer’s disease-associated microglial dysfunction

Roy, N., Haq, I., Ngo, J. C., Bennett, D. A., Teich, A. F., De Jager, P. L., Olah, M., & Sher, F. (2024). Elevated expression of the retrotransposon LINE-1 drives Alzheimer’s disease-associated microglial dysfunction. Acta Neuropathologica, 148(1). https://doi.org/10.1007/s00401-024-02835-6
Authors:
Nainika Roy
Imdadul Haq
Jason C. Ngo
David A. Bennett
Andrew F. Teich
Philip L. De Jager
Marta Olah
Falak Sher
Affiliated Authors:
Nainika Roy
Imdadul Haq
Jason C. Ngo
Andrew F. Teich
Philip L. De Jager
Marta Olah
Falak Sher
Columbia Affiliation:
Subjects:
Alzheimer Disease (MeSH)
Microglia (MeSH)
Long Interspersed Nucleotide Elements (MeSH)
Genome Evolution and Polyploidy in Plants (OpenAlex Topic)
DNA Nanotechnology and Bioanalytical Applications (OpenAlex Topic)
Chitin Metabolism in Insects and Mammals (OpenAlex Topic)
Author Keywords:
alzheimer's disease
microglia
transposable elements
retrotransposons
line-1
neuroinflammation
alzheimer’s disease
elink
Publication Type:
Article
Unique ID:
10.1007/s00401-024-02835-6
PMID:
39604588
DOI:
10.1007/s00401-024-02835-6
Journal:
Acta Neuropathologica
Publication Date:
Data Source:
OpenAlex
Source Link:
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