ISG15-Dependent Stabilisation of USP18 Is Necessary but Not Sufficient to Regulate Type I Interferon Signalling in Humans

Vasou, A., Nightingale, K., Cetkovská, V., Scheler, J., Bamford, C. G. G., Andrejeva, J., Rowe, J. C., Swatek, K. N., Schwarz‐Linek, U., Randall, R. E., McLauchlan, J., Weekes, M. P., Bogunovic, D., & Hughes, D. J. (2025). ISG15‐Dependent Stabilisation of USP18 Is Necessary but Not Sufficient to Regulate Type I Interferon Signalling in Humans. European Journal of Immunology, 55(2). Portico. https://doi.org/10.1002/eji.202451651

Authors:

Andri Vasou

Katie Nightingale

Vladimíra Cetkovská

Jonathan Scheler

Connor G G Bamford

Jelena Andrejeva

Jessica C Rowe

Kirby N Swatek

Ulrich Schwarz-Linek

Richard E Randall

John McLauchlan

Michael P Weekes

Dusan Bogunovic

David J Hughes

Affiliated Authors:

Dusan Bogunovic

Columbia Affiliation:

Vagelos College of Physicians and Surgeons
- Department of Pediatrics

Subjects:

Innate Immunity to Viral Infection (OpenAlex Topic)

Molecular Mechanisms of Inflammasome Activation and Regulation (OpenAlex Topic)

Immunobiology of Dendritic Cells (OpenAlex Topic)

Ubiquitin Thiolesterase (MeSH)

Ubiquitins (MeSH)

Cytokines (MeSH)

Signal Transduction (MeSH)

Interferon Type I (MeSH)

Author Keywords:

autoinflammatory disease

interferon-stimulated genes

interferonopathy

isg15

type i ifn signalling

usp18

interferon‐stimulated genes

Publication Type:

Article

Unique ID:

10.1002/eji.202451651

PMID:

DOI:

10.1002/eji.202451651

Journal:

European Journal of Immunology

Publication Date:

2025-02-11

Data Source:

PubMed

Source Link:

View PubMed Record

View OpenAlex Record

View Scopus Record

View Web of Science Record

Record Created:

Monday, March 3, 2025 - 14:54