HDAC inhibitors engage MITF and the disease-associated microglia signature to enhance amyloid β uptake

Haage, V., Tuddenham, J. F., Bautista, A., Garcia G., F., White, C. C., Patel, R., Comandante-Lou, N., Marshe, V., Griffin, J., Zhou, Y., Ghaffari, D., Acheson, B., Taga, M., St George-Hyslop, P. H., Soni, R. K., Sims, P. A., Menon, V., Sproul, A. A., & De Jager, P. L. (2025). HDAC inhibitors engage MITF and the disease-associated microglia signature to enhance amyloid β uptake. Brain, Behavior, and Immunity, 129, 279–293. https://doi.org/10.1016/j.bbi.2025.05.027
Authors:
Verena Haage
John F Tuddenham
Alex Bautista
Frankie Garcia G
Charles C White
Ronak Patel
Natacha Comandante-Lou
Victoria Marshe
Jennifer Griffin
Ye Zhou
Deniz Ghaffari
Beatrice Acheson
Mariko Taga
Peter H St George-Hyslop
Rajesh Kumar Soni
Peter A Sims
Vilas Menon
Andrew A Sproul
Philip L De Jager
Affiliated Authors:
Verena Haage
John F Tuddenham
Alex Bautista
Frankie Garcia G
Charles C White
Ronak Patel
Natacha Comandante-Lou
Victoria Marshe
Mariko Taga
Peter A Sims
Vilas Menon
Andrew A Sproul
Philip L De Jager
Author Keywords:
disease-associated microglia (dam)
functional analysis
human microglia
in vitro model systems
pharmacological modelling
Publication Type:
Article
Unique ID:
10.1016/j.bbi.2025.05.027
PMID:
Publication Date:
Data Source:
PubMed

Record Created: