Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants

Damotte, V., van der Lee, S. J., Chouraki, V., Grenier‐Boley, B., Simino, J., Adams, H., Tosto, G., White, C., Terzikhan, N., Cruchaga, C., Knol, M. J., Li, S., Schraen, S., Grove, M. L., Satizabal, C., Amin, N., Berr, C., Younkin, S., … van Duijn, C. M. (2021). Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome‐wide association study in over 12,000 non‐demented participants. Alzheimer’s & Dementia, 17(10), 1663–1674. Portico. https://doi.org/10.1002/alz.12333
Authors:
Vincent Damotte
Sven J. van der Lee
Vincent Chouraki
Benjamin Grenier-Boley
Jeannette Simino
Hieab Adams
Giuseppe Tosto
Charles White
Natalie Terzikhan
Carlos Cruchaga
Maria J. Knol
Shuo Li
Susanna Schraen
Megan L. Grove
Claudia Satizabal
Najaf Amin
Claudine Berr
Steven Younkin
Rebecca F. Gottesman
Luc Buée
Alexa Beiser
David S. Knopman
Andre Uitterlinden
Charles DeCarli
Jan Bressler
Anita DeStefano
Jean-François Dartigues
Qiong Yang
Eric Boerwinkle
Christophe Tzourio
Myriam Fornage
M. Arfan Ikram
Philippe Amouyel
Phil de Jager
Christiane Reitz
Thomas H. Mosley
Jean-Charles Lambert
Sudha Seshadri
Cornelia M. van Duijn
Affiliated Authors:
Giuseppe Tosto
Phil de Jager
Christiane Reitz
Columbia Affiliation:
Author Keywords:
alzheimer's disease
apoe
app
bace1
endophenotype
genetic epidemiology
genome‑wide association study
plasma amyloid beta levels
plasma biomarkers
preclinical biomarkers
psen2
elink
Publication Type:
Article
Unique ID:
10.1002/alz.12333
DOI:
10.1002/alz.12333
Journal:
Alzheimer's and Dementia
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record

Record Created: