Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing

Pottier, C., Küçükali, F., Baker, M., Batzler, A., Jenkins, G. D., van Blitterswijk, M., Vicente, C. T., De Coster, W., Wynants, S., Van de Walle, P., Ross, O. A., Murray, M. E., Faura, J., Haggarty, S. J., van Rooij, J. GJ., Mol, M. O., Hsiung, G.-Y. R., Graff, C., Öijerstedt, L., … Rademakers, R. (2025). Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-59216-0
Authors:
Cyril Pottier
Fahri Küçükali
Matt Baker
Anthony Batzler
Gregory D Jenkins
Marka van Blitterswijk
Cristina T Vicente
Wouter De Coster
Sarah Wynants
Pieter Van de Walle
Owen A Ross
Melissa E Murray
Júlia Faura
Stephen J Haggarty
Jeroen Gj van Rooij
Merel O Mol
Ging-Yuek R Hsiung
Caroline Graff
Linn Öijerstedt
Manuela Neumann
Yan Asmann
Shannon K McDonnell
Saurabh Baheti
Keith A Josephs
Jennifer L Whitwell
Kevin F Bieniek
Leah Forsberg
Hilary Heuer
Argentina Lario Lago
Ethan G Geier
Jennifer S Yokoyama
Alexis P Oddi
Margaret Flanagan
Qinwen Mao
John R Hodges
John B Kwok
Kimiko Domoto-Reilly
Matthis Synofzik
Carlo Wilke
Chiadi Onyike
Bradford C Dickerson
Bret M Evers
Brittany N Dugger
David G Munoz
Julia Keith
Lorne Zinman
Ekaterina Rogaeva
EunRan Suh
Tamar Gefen
Changiz Geula
Sandra Weintraub
Janine Diehl-Schmid
Martin R Farlow
Dieter Edbauer
Bryan K Woodruff
Richard J Caselli
Laura L Donker Kaat
Edward D Huey
Eric M Reiman
Simon Mead
Andrew King
Sigrun Roeber
Alissa L Nana
Nilufer Ertekin-Taner
David S Knopman
Ronald C Petersen
Leonard Petrucelli
Ryan J Uitti
Zbigniew K Wszolek
Eliana Marisa Ramos
Lea T Grinberg
Maria Luisa Gorno Tempini
Howard J Rosen
Salvatore Spina
Olivier Piguet
Murray Grossman
John Q Trojanowski
C Dirk Keene
Lee-Way Jin
Johannes Prudlo
Daniel H Geschwind
Robert A Rissman
Carlos Cruchaga
Bernardino Ghetti
Glenda M Halliday
Thomas G Beach
Geidy E Serrano
Thomas Arzberger
Jochen Herms
Adam L Boxer
Lawrence S Honig
Jean P Vonsattel
Oscar L Lopez
Julia Kofler
Charles L White
Marla Gearing
Jonathan Glass
Jonathan D Rohrer
David J Irwin
Edward B Lee
Vivianna Van Deerlin
Rudolph Castellani
Marsel M Mesulam
Maria C Tartaglia
Elizabeth C Finger
Claire Troakes
Safa Al-Sarraj
Clifton L Dalgard
Bruce L Miller
Harro Seelaar
Neill R Graff-Radford
Bradley F Boeve
Ian Ra Mackenzie
John C van Swieten
William W Seeley
Kristel Sleegers
Dennis W Dickson
Joanna M Biernacka
Rosa Rademakers
Affiliated Authors:
Lawrence S Honig
Jean P Vonsattel
Columbia Affiliation:
Subjects:
Genetic Predisposition to Disease (MeSH)
Frontotemporal Lobar Degeneration (MeSH)
DNA-Binding Proteins (MeSH)
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Publication Type:
Article
Unique ID:
10.1038/s41467-025-59216-0
PMID:
40280976
DOI:
10.1038/s41467-025-59216-0
Journal:
Nature Communications
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

Record Created: