KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease

Neitzel, J., Franzmeier, N., Rubinski, A., Dichgans, M., Brendel, M., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Shaw, L. M., Liu, E., … Ewers, M. (2021). KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-23755-z
Authors:
Julia Neitzel
Nicolai Franzmeier
Anna Rubinski
Martin Dichgans
Matthias Brendel
Michael Weiner
Paul Aisen
Ronald Petersen
Clifford R. Jack
William Jagust
John Q. Trojanowki
Arthur W. Toga
Laurel Beckett
Robert C. Green
Andrew J. Saykin
John Morris
Leslie M. Shaw
Enchi Liu
Tom Montine
Ronald G. Thomas
Michael Donohue
Sarah Walter
Devon Gessert
Tamie Sather
Gus Jiminez
Danielle Harvey
Matthew Bernstein
Nick Fox
Paul Thompson
Norbert Schuff
Charles DeCArli
Bret Borowski
Jeff Gunter
Matt Senjem
Prashanthi Vemuri
David Jones
Kejal Kantarci
Chad Ward
Robert A. Koeppe
Norm Foster
Eric M. Reiman
Kewei Chen
Chet Mathis
Susan Landau
Nigel J. Cairns
Erin Householder
Lisa Taylor Reinwald
Virginia Lee
Magdalena Korecka
Michal Figurski
Karen Crawford
Scott Neu
Tatiana M. Foroud
Steven Potkin
Li Shen
Faber Kelley
Sungeun Kim
Kwangsik Nho
Zaven Kachaturian
Richard Frank
Peter J. Snyder
Susan Molchan
Jeffrey Kaye
Joseph Quinn
Betty Lind
Raina Carter
Sara Dolen
Lon S. Schneider
Sonia Pawluczyk
Mauricio Beccera
Liberty Teodoro
Bryan M. Spann
James Brewer
Helen Vanderswag
Adam Fleisher
Judith L. Heidebrink
Joanne L. Lord
Sara S. Mason
Colleen S. Albers
David Knopman
Kris Johnson
Rachelle S. Doody
Javier Villanueva Meyer
Munir Chowdhury
Susan Rountree
Mimi Dang
Yaakov Stern
Lawrence S. Honig
Karen L. Bell
Beau Ances
Maria Carroll
Sue Leon
Mark A. Mintun
Stacy Schneider
Angela OliverNG
Randall Griffith
David Clark
David Geldmacher
John Brockington
Erik Roberson
Hillel Grossman
Effie Mitsis
Leyla deToledo-Morrell
Raj C. Shah
Ranjan Duara
Daniel Varon
Maria T. Greig
Peggy Roberts
Marilyn Albert
Chiadi Onyike
Daniel D’Agostino
Stephanie Kielb
James E. Galvin
Dana M. Pogorelec
Brittany Cerbone
Christina A. Michel
Henry Rusinek
Mony J. de Leon
Lidia Glodzik
Susan De Santi
P. Murali Doraiswamy
Jeffrey R. Petrella
Terence Z. Wong
Steven E. Arnold
Jason H. Karlawish
David Wolk
Charles D. Smith
Greg Jicha
Peter Hardy
Partha Sinha
Elizabeth Oates
Gary Conrad
Oscar L. Lopez
MaryAnn Oakley
Donna M. Simpson
Anton P. Porsteinsson
Bonnie S. Goldstein
Kim Martin
Kelly M. Makino
M. Saleem Ismail
Connie Brand
Ruth A. Mulnard
Gaby Thai
Catherine Mc Adams Ortiz
Kyle Womack
Dana Mathews
Mary Quiceno
Ramon Diaz Arrastia
Richard King
Myron Weiner
Kristen Martin Cook
Michael DeVous
Allan I. Levey
James J. Lah
Janet S. Cellar
Jeffrey M. Burns
Heather S. Anderson
Russell H. Swerdlow
Liana Apostolova
Kathleen Tingus
Ellen Woo
Daniel H. S. Silverman
Po H. Lu
George Bartzokis
Neill R. Graff Radford
Francine ParfittH
Tracy Kendall
Heather Johnson
Martin R. Farlow
Ann Marie Hake
Brandy R. Matthews
Scott Herring
Cynthia Hunt
Christopher H. van Dyck
Richard E. Carson
Martha G. MacAvoy
Howard Chertkow
Howard Bergman
Chris Hosein
Sandra Black
Bojana Stefanovic
Curtis Caldwell
Ging Yuek Robin Hsiung
Howard Feldman
Benita Mudge
Michele Assaly Past
Andrew Kertesz
John Rogers
Dick Trost
Charles Bernick
Donna Munic
Diana Kerwin
Marek Marsel Mesulam
Kristine Lipowski
Chuang Kuo Wu
Nancy Johnson
Carl Sadowsky
Walter Martinez
Teresa Villena
Raymond Scott Turner
Kathleen Johnson
Brigid Reynolds
Reisa A. Sperling
Keith A. Johnson
Gad Marshall
Meghan Frey
Jerome Yesavage
Joy L. Taylor
Barton Lane
Allyson Rosen
Jared Tinklenberg
Marwan N. Sabbagh
Christine M. Belden
Sandra A. Jacobson
Sherye A. Sirrel
Neil Kowall
Ronald Killiany
Andrew E. Budson
Alexander Norbash
Patricia Lynn Johnson
Thomas O. Obisesan
Saba Wolday
Joanne Allard
Alan Lerner
Paula Ogrocki
Leon Hudson
Evan Fletcher
Owen Carmichael
John Olichney
Smita Kittur
Michael Borrie
T.Y. Lee
Rob Bartha
Sterling Johnson
Sanjay Asthana
Cynthia M. Carlsson
Adrian Preda
Dana Nguyen
Pierre Tariot
Stephanie Reeder
Vernice Bates
Horacio Capote
Michelle Rainka
Douglas W. Scharre
Maria Kataki
Anahita Adeli
Earl A. Zimmerman
Dzintra Celmins
Alice D. Brown
Godfrey D. Pearlson
Karen Blank
Karen Anderson
Robert B. Santulli
Tamar J. Kitzmiller
Eben S. Schwartz
Kaycee M. SinkS
Jeff D. Williamson
Pradeep Garg
Franklin Watkins
Brian R. Ott
Henry Querfurth
Geoffrey Tremont
Stephen Salloway
Paul Malloy
Stephen Correia
Howard J. Rosen
Bruce L. Miller
Jacobo Mintzer
Kenneth Spicer
David Bachman
Elizabether Finger
Stephen Pasternak
Irina Rachinsky
Dick Drost
Nunzio Pomara
Raymundo Hernando
Antero Sarrael
Susan K. Schultz
Laura L. Boles Ponto
Hyungsub Shim
Karen Elizabeth Smith
Norman Relkin
Gloria Chaing
Lisa Raudin
Amanda Smith
Kristin Fargher
Balebail Ashok Raj
Rainer Malik
Michael Ewers
Affiliated Authors:
Yaakov Stern
Lawrence S. Honig
Karen L. Bell
Columbia Affiliation:
elink
Publication Type:
Article
Unique ID:
10.1038/s41467-021-23755-z
PMID:
34158479
DOI:
10.1038/s41467-021-23755-z
Journal:
Nature Communications
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record

Record Created: