Safety, tolerability, pharmacokinetics, and antimalarial activity of MMV533: a phase 1a first-in-human, randomised, ascending dose and food effect study, and a phase 1b Plasmodium falciparum volunteer infection study

Bestgen, B., Jones, S., Thathy, V., Kuemmerle, A., Barcelo, C., Haouala, A., Gossen, D., Marx, M. W., Di Resta, I., Szramowska, M., Webster, R. A., Llewellyn, S., Ritacco, D. A., Yeo, T., Leroy, D., Barber, B. E., Fidock, D. A., Griffin, P., Lickliter, J., & Chalon, S. (2024). Safety, tolerability, pharmacokinetics, and antimalarial activity of MMV533: a phase 1a first-in-human, randomised, ascending dose and food effect study, and a phase 1b Plasmodium falciparum volunteer infection study. The Lancet Infectious Diseases. https://doi.org/10.1016/s1473-3099(24)00664-9
Authors:
Benoît Bestgen
Sam Jones
Vandana Thathy
Andrea Kuemmerle
Catalina Barceló
Amina Haouala
Denis Gossen
Michael W. Marx
Ilaria Di Resta
Maja Szramowska
Rebecca Webster
Stacey Llewellyn
Dominic A. Ritacco
Tomas Yeo
Didier Leroy
Bridget E. Barber
David A. Fidock
Paul Griffin
Jason D. Lickliter
Stephan Chalon
Affiliated Authors:
Vandana Thathy
Dominic A. Ritacco
Tomas Yeo
David A. Fidock
Publication Type:
Article
Unique ID:
10.1016/s1473-3099(24)00664-9
PMID:
Publication Date:
Data Source:
OpenAlex

Record Created: