A multidonor class of highly glycan-dependent HIV-1 gp120-gp41 interface-targeting broadly neutralizing antibodies

Cale, E. M., Shen, C.-H., Olia, A. S., Radakovich, N. A., Rawi, R., Yang, Y., Ambrozak, D. R., Bennici, A. K., Chuang, G.-Y., Crooks, E. D., Driscoll, J. I., Lin, B. C., Louder, M. K., Madden, P. J., Messina, M. A., Osawa, K., Stewart-Jones, G. B. E., Verardi, R., Vrakas, Z., … Gorman, J. (2024). A multidonor class of highly glycan-dependent HIV-1 gp120-gp41 interface-targeting broadly neutralizing antibodies. Cell Reports, 43(12), 115010. https://doi.org/10.1016/j.celrep.2024.115010
Authors:
Evan M Cale
Chen-Hsiang Shen
Adam S Olia
Nathan A Radakovich
Reda Rawi
Yongping Yang
David R Ambrozak
Anthony K Bennici
Gwo-Yu Chuang
Emma D Crooks
Jefferson I Driscoll
Bob C Lin
Mark K Louder
Patrick J Madden
Michael A Messina
Keiko Osawa
Guillaume B E Stewart-Jones
Raffaello Verardi
Zoe Vrakas
Danielle Xie
Baoshan Zhang
James M Binley
Mark Connors
Richard A Koup
Theodore C Pierson
Nicole A Doria-Rose
Peter D Kwong
John R Mascola
Jason Gorman
Affiliated Authors:
Peter D Kwong
Columbia Affiliation:
Subjects:
HIV Envelope Protein gp120 (MeSH)
Polysaccharides (MeSH)
HIV-1 (MeSH)
Antibodies, Neutralizing (MeSH)
HIV Envelope Protein gp41 (MeSH)
Author Keywords:
35o22
broadly neutralizing antibody
cp: immunology
cp: molecular biology
glycan
hiv-1 envelope trimer
multidonor antibody class
n90
subunit interface
elink
Publication Type:
Article
Unique ID:
10.1016/j.celrep.2024.115010
PMID:
39675002
DOI:
10.1016/j.celrep.2024.115010
Journal:
Cell Reports
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created: