Deciphering proteins in Alzheimer's disease: A new Mendelian randomization method integrated with AlphaFold3 for 3D structure prediction

Yao, M., Miller, G. W., Vardarajan, B. N., Baccarelli, A. A., Guo, Z., & Liu, Z. (2024). Deciphering proteins in Alzheimer’s disease: A new Mendelian randomization method integrated with AlphaFold3 for 3D structure prediction. Cell Genomics, 4(12), 100700. https://doi.org/10.1016/j.xgen.2024.100700
Authors:
Minhao Yao
Gary W Miller
Badri N Vardarajan
Andrea A Baccarelli
Zijian Guo
Zhonghua Liu
Affiliated Authors:
Gary W Miller
Badri N Vardarajan
Zhonghua Liu
Columbia Affiliation:
Subjects:
Alzheimer Disease (MeSH)
Mendelian Randomization Analysis (MeSH)
Genome-Wide Association Study (MeSH)
Quantitative Trait Loci (MeSH)
Author Keywords:
3d structure
alphafold3
alzheimer's disease
causal inference
genome-wide association study
instrumental variable
mendelian randomization
missense variants
pqtl
proteomics
elink
Publication Type:
Article
Unique ID:
10.1016/j.xgen.2024.100700
PMID:
39637861
DOI:
10.1016/j.xgen.2024.100700
Journal:
Cell Genomics
Publication Date:
Data Source:
PubMed
Source Link:
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