Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia

Baran, N., Lodi, A., Dhungana, Y., Herbrich, S., Collins, M., Sweeney, S., Pandey, R., Skwarska, A., Patel, S., Tremblay, M., Kuruvilla, V. M., Cavazos, A., Kaplan, M., Warmoes, M. O., Veiga, D. T., Furudate, K., Rojas-Sutterin, S., Haman, A., Gareau, Y., … Konopleva, M. (2022). Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30396-3
Authors:
Natalia Baran
Alessia Lodi
Yogesh Dhungana
Shelley Herbrich
Meghan Collins
Shannon Sweeney
Renu Pandey
Anna Skwarska
Shraddha Patel
Mathieu Tremblay
Vinitha Mary Kuruvilla
Antonio Cavazos
Mecit Kaplan
Marc O. Warmoes
Diogo Troggian Veiga
Ken Furudate
Shanti Rojas-Sutterin
Andre Haman
Yves Gareau
Anne Marinier
Helen Ma
Karine Harutyunyan
May Daher
Luciana Melo Garcia
Gheath Al-Atrash
Sujan Piya
Vivian Ruvolo
Wentao Yang
Sriram Saravanan Shanmugavelandy
Ningping Feng
Jason Gay
Di Du
Jun J. Yang
Fieke W. Hoff
Marcin Kaminski
Katarzyna Tomczak
R. Eric Davis
Daniel Herranz
Adolfo Ferrando
Elias J. Jabbour
M. Emilia Di Francesco
David T. Teachey
Terzah M. Horton
Steven Kornblau
Katayoun Rezvani
Guy Sauvageau
Mihai Gagea
Michael Andreeff
Koichi Takahashi
Joseph R. Marszalek
Philip L. Lorenzi
Jiyang Yu
Stefano Tiziani
Trang Hoang
Marina Konopleva
Affiliated Authors:
Adolfo Ferrando
Columbia Affiliation:
Subjects:
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (MeSH)
Metabolic Reprogramming in Cancer Biology (OpenAlex Topic)
Epigenetic Modifications and Their Functional Implications (OpenAlex Topic)
RNA Methylation and Modification in Gene Expression (OpenAlex Topic)
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Publication Type:
Article
Unique ID:
10.1038/s41467-022-30396-3
PMID:
35589701
DOI:
10.1038/s41467-022-30396-3
Journal:
Nature Communications
Publication Date:
Data Source:
Scopus
Source Link:
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