Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes

Kitamoto, T., Lee, Y.-K., Sultana, N., Watanabe, H., McKimpson, W. M., Du, W., Fan, J., Diaz, B., Lin, H. V., Leibel, R. L., Belvedere, S., & Accili, D. (2022). Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes. Molecular Metabolism, 66, 101624. https://doi.org/10.1016/j.molmet.2022.101624
Authors:
Takumi Kitamoto
Yun-Kyoung Lee
Nishat Sultana
Hitoshi Watanabe
Wendy M McKimpson
Wen Du
Jason Fan
Bryan Diaz
Hua V Lin
Rudolph L Leibel
Sandro Belvedere
Domenico Accili
Affiliated Authors:
Takumi Kitamoto
Nishat Sultana
Hitoshi Watanabe
Wendy M McKimpson
Wen Du
Bryan Diaz
Rudolph L Leibel
Domenico Accili
Columbia Affiliation:
Subjects:
Diabetes Mellitus (MeSH)
Insulin-Secreting Cells (MeSH)
Author Keywords:
diabetes
insulin
? cell replacement
foxo1
foxo1 inhibitor
notch inhibition
β cell replacement
elink
Publication Type:
Article
Unique ID:
10.1016/j.molmet.2022.101624
PMID:
36341906
DOI:
10.1016/j.molmet.2022.101624
Journal:
Molecular Metabolism
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created: