Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues

Limone, F., Guerra San Juan, I., Mitchell, J. M., Smith, J. L. M., Raghunathan, K., Meyer, D., Ghosh, S. D., Couto, A., Klim, J. R., Joseph, B. J., Gold, J., Mello, C. J., Nemesh, J., Smith, B. M., Verhage, M., McCarroll, S. A., Pietiläinen, O., Nehme, R., & Eggan, K. (2023). Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues. Cell Reports, 42(1), 111896. https://doi.org/10.1016/j.celrep.2022.111896
Authors:
Francesco Limone
Irune Guerra San Juan
Jana M. Mitchell
Janell L.M. Smith
Kavya Raghunathan
Daniel Meyer
Sulagna Ghosh
Alexander Benavides Couto
Joseph R. Klim
Brian Joseph
John T. Gold
Curtis J. Mello
James Nemesh
Brittany M. Curtiss
Matthijs Verhage
Steven A. McCarroll
Olli Pietiläinen
Ralda Nehme
Kevin Eggan
Affiliated Authors:
Brian Joseph
Author Keywords:
cp: neuroscience
cp: stem cell research
differentiation protocol
dropulation
human stem cells
motor neuron
multiplexed pooled sequencing
neuronal differentiation
ngn2
patterning molecules
single cell profiling
spinal cord
Publication Type:
Article
Unique ID:
10.1016/j.celrep.2022.111896
PMID:
Journal:
Publication Date:
Data Source:
OpenAlex

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