U01HL098188

NIH – National Heart, Lung, and Blood Institute

Visit this grant

Association of genetic and sulcal traits with executive function in congenital heart disease

Maleyeff, L., Newburger, J. W., Wypij, D., Thomas, N. H., Anagnoustou, E., Brueckner, M., Chung, W. K., Cleveland, J., Cunningham, S., Gelb, B. D., Goldmuntz, E., Hagler, D. J., Huang, H., King, E., McQuillen, P., Miller, T. A., Norris‐Brilliant, A., Porter, G. A., Roberts, A. E., … Morton, S. U. (2023). Association of genetic and sulcal traits with executive function in congenital heart disease. Annals of Clinical and Translational Neurology, 11(2), 278–290. Portico. https://doi.org/10.1002/acn3.51950
Authors:
Lara Maleyeff
Jane W Newburger
David Wypij
Nina H Thomas
Evdokia Anagnoustou
Martina Brueckner
Wendy K Chung
John Cleveland
Sean Cunningham
Bruce D Gelb
Elizabeth Goldmuntz
Donald J Hagler
Hao Huang
Eileen King
Patrick McQuillen
Thomas A Miller
Ami Norris-Brilliant
George A Porter
Amy E Roberts
P Ellen Grant
Kiho Im
Sarah U Morton
Affiliated Authors:
Wendy K Chung
Columbia Affiliation:
Subjects:
Epidemiology and Management of Congenital Heart Disease (OpenAlex Topic)
Molecular Mechanisms of Cardiac Development and Regeneration (OpenAlex Topic)
Congenital Coronary Artery Anomalies and Their Management (OpenAlex Topic)
Executive Function (MeSH)
Heart Defects, Congenital (MeSH)
Grants:
P50HD105351 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
UL1TR002541 (NIH – National Center for Advancing Translational Sciences)
UL1TR001863 (NIH – National Center for Advancing Translational Sciences)
UL1TR000003 (NIH – National Center for Advancing Translational Sciences)
U01HL098162 (NIH – National Heart, Lung, and Blood Institute)
U01HL098163 (NIH – National Heart, Lung, and Blood Institute)
U01HL098147 (NIH – National Heart, Lung, and Blood Institute)
U01HL131003 (NIH – National Heart, Lung, and Blood Institute)
U01HL098188 (NIH – National Heart, Lung, and Blood Institute)
U01HL098153 (NIH – National Heart, Lung, and Blood Institute)
R01HL128818 (NIH – National Heart, Lung, and Blood Institute)
U01HL098123 (NIH – National Heart, Lung, and Blood Institute)
K08HL157653 (NIH – National Heart, Lung, and Blood Institute)
U54HG006504 (NIH – National Human Genome Research Institute)
R01NS114087 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1002/acn3.51950
PMID:
38009418
DOI:
10.1002/acn3.51950
Journal:
Annals of Clinical and Translational Neurology
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record
View OpenAlex Record

Record Created:

Evidence-Based Assessment of Congenital Heart Disease Genes to Enable Returning Results in a Genomic Study

Griffin, E. L., Nees, S. N., Morton, S. U., Wynn, J., Patel, N., Jobanputra, V., Robinson, S., Kochav, S. M., Tao, A., Andrews, C., Cross, N., Geva, J., Lanzilotta, K., Ritter, A., Taillie, E., Thompson, A., Meyer, C., Akers, R., King, E. C., … Chung, W. K. (2023). Evidence-Based Assessment of Congenital Heart Disease Genes to Enable Returning Results in a Genomic Study. Circulation: Genomic and Precision Medicine, 16(2). https://doi.org/10.1161/circgen.122.003791
Authors:
Emily Griffin
Shannon N. Nees
Sarah U. Morton
Julia Wynn
Nihir Patel
Vaidehi Jobanputra
Scott Robinson
Stephanie M. Kochav
Alice Tao
Carli Andrews
Nancy Cross
Judith Geva
Kristen Lanzilotta
Alyssa Ritter
Eileen Taillie
Alexandra Thompson
J-P. Meyer
Rachel Akers
Eileen King
James Cnota
Richard W. Kim
George A. Porter
Martina Brueckner
Christine E. Seidman
Yufeng Shen
Bruce D. Gelb
Elizabeth Goldmuntz
Jane W. Newburger
Amy E. Roberts
Wendy K. Chung
Affiliated Authors:
Emily Griffin
Julia Wynn
Vaidehi Jobanputra
Scott Robinson
Stephanie M. Kochav
Carli Andrews
Alexandra Thompson
Yufeng Shen
Wendy K. Chung
Columbia Affiliation:
Subjects:
Heart Defects, Congenital (MeSH)
Epidemiology and Management of Congenital Heart Disease (OpenAlex Topic)
Molecular Mechanisms of Cardiac Development and Regeneration (OpenAlex Topic)
Surgical Ventricular Reconstruction in Myocardial Infarction (OpenAlex Topic)
Author Keywords:
clingen
congenital heart disease
gene curation
Grants:
UM1HL128711 (NIH – National Heart, Lung, and Blood Institute)
U01HL153009 (NIH – National Heart, Lung, and Blood Institute)
U01HL098123 (NIH – National Heart, Lung, and Blood Institute)
U01HL098153 (NIH – National Heart, Lung, and Blood Institute)
U01HL098163 (NIH – National Heart, Lung, and Blood Institute)
UM1HL098123 (NIH – National Heart, Lung, and Blood Institute)
UM1HL128761 (NIH – National Heart, Lung, and Blood Institute)
U01HL131003 (NIH – National Heart, Lung, and Blood Institute)
U01HL098188 (NIH – National Heart, Lung, and Blood Institute)
UM1HL098147 (NIH – National Heart, Lung, and Blood Institute)
U01HL098162 (NIH – National Heart, Lung, and Blood Institute)
U01HL098147 (NIH – National Heart, Lung, and Blood Institute)
UM1HL098162 (NIH – National Heart, Lung, and Blood Institute)
T32HL007854 (NIH – National Heart, Lung, and Blood Institute)
Publication Type:
Article
Unique ID:
10.1161/circgen.122.003791
PMID:
36803080
DOI:
10.1161/circgen.122.003791
Journal:
Circulation: Genomic and Precision Medicine
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
View PubMed Record
View Scopus Record

Record Created:

Association of Potentially Damaging De Novo Gene Variants With Neurologic Outcomes in Congenital Heart Disease

Morton, S. U., Norris-Brilliant, A., Cunningham, S., King, E., Goldmuntz, E., Brueckner, M., Miller, T. A., Thomas, N. H., Liu, C., Adams, H. R., Bellinger, D. C., Cleveland, J., Cnota, J. F., Dale, A. M., Frommelt, M., Gelb, B. D., Grant, P. E., Goldberg, C. S., Huang, H., … Newburger, J. W. (2023). Association of Potentially Damaging De Novo Gene Variants With Neurologic Outcomes in Congenital Heart Disease. JAMA Network Open, 6(1), e2253191. https://doi.org/10.1001/jamanetworkopen.2022.53191
Authors:
Sarah U. Morton
Ami Norris‐Brilliant
Sean Cunningham
Eileen King
Elizabeth Goldmuntz
Martina Brueckner
Thomas A. Miller
Nina H. Thomas
Chunyan Liu
Heather Adams
David C. Bellinger
Jeanette N. Cleveland
James Cnota
Anders M. Dale
Michele A. Frommelt
Bruce D. Gelb
P. Ellen Grant
Caren S. Goldberg
Hao Huang
Joshua Kuperman
Jennifer S. Li
Patrick S. McQuillen
Ashok Panigrahy
George A. Porter
Amy E. Roberts
Mark W. Russell
Christine E. Seidman
Madalina E. Tivarus
Evdokia Anagnoustou
Donald J. Hagler
Wendy K. Chung
Jane W. Newburger
Affiliated Authors:
Wendy K. Chung
Columbia Affiliation:
Subjects:
Autism Spectrum Disorder (MeSH)
Heart Defects, Congenital (MeSH)
Epidemiology and Management of Congenital Heart Disease (OpenAlex Topic)
Molecular Mechanisms of Cardiac Development and Regeneration (OpenAlex Topic)
Congenital Coronary Artery Anomalies and Their Management (OpenAlex Topic)
Grants:
P50HD105351 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
UL1TR000003 (NIH – National Center for Advancing Translational Sciences)
UL1TR001863 (NIH – National Center for Advancing Translational Sciences)
U01HL098123 (NIH – National Heart, Lung, and Blood Institute)
U01HL098147 (NIH – National Heart, Lung, and Blood Institute)
UG1HL135685 (NIH – National Heart, Lung, and Blood Institute)
U24HL135691 (NIH – National Heart, Lung, and Blood Institute)
U01HL098162 (NIH – National Heart, Lung, and Blood Institute)
U01HL098153 (NIH – National Heart, Lung, and Blood Institute)
U01HL131003 (NIH – National Heart, Lung, and Blood Institute)
R01HL128818 (NIH – National Heart, Lung, and Blood Institute)
U01HL098163 (NIH – National Heart, Lung, and Blood Institute)
U01HL098188 (NIH – National Heart, Lung, and Blood Institute)
U54HG006504 (NIH – National Human Genome Research Institute)
R01MH092535 (NIH – National Institute of Mental Health)
Publication Type:
Article
Unique ID:
10.1001/jamanetworkopen.2022.53191
PMID:
36701153
DOI:
10.1001/jamanetworkopen.2022.53191
Journal:
JAMA Network Open
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
View PubMed Record
View Scopus Record
View Web of Science Record

Record Created:

Neither cardiac mitochondrial DNA variation nor copy number contribute to congenital heart disease risk

Willcox, J. A. L., Geiger, J. T., Morton, S. U., McKean, D., Quiat, D., Gorham, J. M., Tai, A. C., DePalma, S., Bernstein, D., Brueckner, M., Chung, W. K., Giardini, A., Goldmuntz, E., Kaltman, J. R., Kim, R., Newburger, J. W., Shen, Y., Srivastava, D., Tristani-Firouzi, M., … Seidman, C. E. (2022). Neither cardiac mitochondrial DNA variation nor copy number contribute to congenital heart disease risk. The American Journal of Human Genetics, 109(5), 961–966. https://doi.org/10.1016/j.ajhg.2022.03.011
Authors:
Jon A.L. Willcox
Joshua T. Geiger
Sarah U. Morton
David McKean
Daniel Quiat
Joshua M. Gorham
Angela C. Tai
Steven DePalma
Daniel Bernstein
Martina Brueckner
Wendy K. Chung
Alessandro Giardini
Elizabeth Goldmuntz
Jonathan R. Kaltman
Richard Kim
Jane W. Newburger
Yufeng Shen
Deepak Srivastava
Martin Tristani-Firouzi
Bruce Gelb
George A. Porter
J.G. Seidman
Christine E. Seidman
Affiliated Authors:
Wendy K. Chung
Yufeng Shen
Columbia Affiliation:
Subjects:
DNA, Mitochondrial (MeSH)
Heart Defects, Congenital (MeSH)
Mitochondrial Dynamics and Reactive Oxygen Species Regulation (OpenAlex Topic)
Standards and Guidelines for Genetic Variant Interpretation (OpenAlex Topic)
Molecular Mechanisms of Cardiac Development and Regeneration (OpenAlex Topic)
Author Keywords:
congenital heart disease
genome sequencing
mitochondrial copy number
mitochondrial genome
Grants:
P50HD105351 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
UM1HL098162 (NIH – National Heart, Lung, and Blood Institute)
R03HL150412 (NIH – National Heart, Lung, and Blood Institute)
UM1HL128711 (NIH – National Heart, Lung, and Blood Institute)
U01HL098188 (NIH – National Heart, Lung, and Blood Institute)
R01HL144776 (NIH – National Heart, Lung, and Blood Institute)
U01HL098163 (NIH – National Heart, Lung, and Blood Institute)
U01HL098147 (NIH – National Heart, Lung, and Blood Institute)
U01HL131003 (NIH – National Heart, Lung, and Blood Institute)
R01HL084553 (NIH – National Heart, Lung, and Blood Institute)
UM1HL128761 (NIH – National Heart, Lung, and Blood Institute)
U01HL098153 (NIH – National Heart, Lung, and Blood Institute)
R01HL080494 (NIH – National Heart, Lung, and Blood Institute)
UM1HL098123 (NIH – National Heart, Lung, and Blood Institute)
UM1HL098147 (NIH – National Heart, Lung, and Blood Institute)
Publication Type:
Article
Unique ID:
10.1016/j.ajhg.2022.03.011
PMID:
35397206
DOI:
10.1016/j.ajhg.2022.03.011
Journal:
American Journal of Human Genetics
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View Web of Science Record
View OpenAlex Record
View PubMed Record

Record Created:

Genome-Wide De Novo Variants in Congenital Heart Disease Are Not Associated With Maternal Diabetes or Obesity

Morton, S. U., Pereira, A. C., Quiat, D., Richter, F., Kitaygorodsky, A., Hagen, J., Bernstein, D., Brueckner, M., Goldmuntz, E., Kim, R. W., Lifton, R. P., Porter, G. A., Tristani-Firouzi, M., Chung, W. K., Roberts, A., Gelb, B. D., Shen, Y., Newburger, J. W., Seidman, J. G., & Seidman, C. E. (2022). Genome-Wide De Novo Variants in Congenital Heart Disease Are Not Associated With Maternal Diabetes or Obesity. Circulation: Genomic and Precision Medicine, 15(2). https://doi.org/10.1161/circgen.121.003500
Authors:
Sarah U. Morton
Alexandre C. Pereira
Daniel Quiat
Felix Richter
Alexander Kitaygorodsky
Jacob Hagen
Daniel Bernstein
Martina Brueckner
Elizabeth Goldmuntz
Richard W. Kim
Richard P. Lifton
George A. Porter
Martin Tristani-Firouzi
Wendy K. Chung
Amy Roberts
Bruce D. Gelb
Yufeng Shen
Jane W. Newburger
J.G. Seidman
Christine E. Seidman
Affiliated Authors:
Alexander Kitaygorodsky
Jacob Hagen
Wendy K. Chung
Yufeng Shen
Columbia Affiliation:
Subjects:
Diabetes Mellitus (MeSH)
Heart Defects, Congenital (MeSH)
Epidemiology and Management of Congenital Heart Disease (OpenAlex Topic)
Molecular Mechanisms of Cardiac Development and Regeneration (OpenAlex Topic)
Surgical Ventricular Reconstruction in Myocardial Infarction (OpenAlex Topic)
Author Keywords:
body mass index
genome
heart defects, congenital
obesity
prevalence
congenital
heart defects
Grants:
UL1TR001863 (NIH – National Center for Advancing Translational Sciences)
UL1TR000003 (NIH – National Center for Advancing Translational Sciences)
UM1HL098147 (NIH – National Heart, Lung, and Blood Institute)
U01HL098153 (NIH – National Heart, Lung, and Blood Institute)
U01HL098147 (NIH – National Heart, Lung, and Blood Institute)
U01HL098163 (NIH – National Heart, Lung, and Blood Institute)
R03HL150412 (NIH – National Heart, Lung, and Blood Institute)
U01HL098123 (NIH – National Heart, Lung, and Blood Institute)
U01HL131003 (NIH – National Heart, Lung, and Blood Institute)
U01HL098188 (NIH – National Heart, Lung, and Blood Institute)
P20HL101408 (NIH – National Heart, Lung, and Blood Institute)
U54HG006504 (NIH – National Human Genome Research Institute)
Publication Type:
Article
Unique ID:
10.1161/CIRCGEN.121.003500
PMID:
35130025
DOI:
10.1161/CIRCGEN.121.003500
Journal:
Circulation: Genomic and Precision Medicine
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View Web of Science Record
View OpenAlex Record
View PubMed Record

Record Created:

Common Genetic Variants Contribute to Risk of Transposition of the Great Arteries

Škorić-Milosavljević, D., Tadros, R., Bosada, F. M., Tessadori, F., van Weerd, J. H., Woudstra, O. I., Tjong, F. V. Y., Lahrouchi, N., Bajolle, F., Cordell, H. J., Agopian, A. J., Blue, G. M., Barge-Schaapveld, D. Q. C. M., Gewillig, M., Preuss, C., Lodder, E. M., Barnett, P., Ilgun, A., Beekman, L., … Bezzina, C. R. (2022). Common Genetic Variants Contribute to Risk of Transposition of the Great Arteries. Circulation Research, 130(2), 166–180. https://doi.org/10.1161/circresaha.120.317107
Authors:
Doris Škorić-Milosavljević
Rafik Tadros
Fernanda M. Bosada
Federico Tessadori
Jan Hendrik Van Weerd
Odilia I. Woudstra
Fleur V.Y. Tjong
Najim Lahrouchi
Fanny Bajolle
Heather J. Cordell
A.J. Agopian
Gillian M. Blue
Daniela Q.C.M. Barge-Schaapveld
Marc Gewillig
Christoph Preuss
Elisabeth M. Lodder
Phil Barnett
Aho Ilgun
Leander Beekman
Karel Van Duijvenboden
Regina Bokenkamp
Martina Müller-Nurasyid
Hubert W. Vliegen
Thelma C. Konings
Joost P. Van Melle
Arie P.J. Van Dijk
Roland R.J. Van Kimmenade
Jolien W. Roos-Hesselink
Gertjan T. Sieswerda
Folkert Meijboom
Hashim Abdul-Khaliq
Felix Berger
Sven Dittrich
Marc-Phillip Hitz
Julia Moosmann
Frank-Thomas Riede
Stephan Schubert
Pilar Galan
Mark Lathrop
Hans M. Munter
Ammar Al-Chalabi
Christopher E. Shaw
Pamela J. Shaw
Karen E. Morrison
Jan H. Veldink
Leonard H. Van Den Berg
Sylvia Evans
Marcelo A. Nobrega
Ivy Aneas
Milena Radivojkov-Blagojević
Thomas Meitinger
Erwin Oechslin
Tapas Mondal
Lynn Bergin
John F. Smythe
Luis Altamirano-Diaz
Jane Lougheed
Berto J. Bouma
Marie-A. Chaix
Jennie Kline
Anne S. Bassett
Gregor Andelfinger
Roel L.F. Van Der Palen
Patrice Bouvagnet
Sally-Ann B. Clur
Jeroen Breckpot
Wilhelmina S. Kerstjens-Frederikse
David S. Winlaw
Ulrike M.M. Bauer
Seema Mital
Elizabeth Goldmuntz
Bernard Keavney
Damien Bonnet
Barbara J. Mulder
Michael W.T. Tanck
Jeroen Bakkers
Vincent M. Christoffels
Cornelis J. Boogerd
Alex V. Postma
Connie R. Bezzina
Affiliated Authors:
Jennie Kline
Columbia Affiliation:
Subjects:
Polymorphism, Single Nucleotide (MeSH)
Transposition of Great Vessels (MeSH)
Author Keywords:
wnt-5a protein
congenital heart disease
genome-wide association study
single nucleotide polymorphism
transposition of great vessels
Grants:
P01HD070454 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
UL1TR000003 (NIH – National Center for Advancing Translational Sciences)
UM1HL098162 (NIH – National Heart, Lung, and Blood Institute)
UM1HL128711 (NIH – National Heart, Lung, and Blood Institute)
UM1HL128761 (NIH – National Heart, Lung, and Blood Institute)
U01HL098163 (NIH – National Heart, Lung, and Blood Institute)
U01HL131003 (NIH – National Heart, Lung, and Blood Institute)
U01HL098188 (NIH – National Heart, Lung, and Blood Institute)
U01HL098123 (NIH – National Heart, Lung, and Blood Institute)
UM1HL098123 (NIH – National Heart, Lung, and Blood Institute)
U01HL098162 (NIH – National Heart, Lung, and Blood Institute)
U01HL098147 (NIH – National Heart, Lung, and Blood Institute)
U01HL098153 (NIH – National Heart, Lung, and Blood Institute)
UM1HL098147 (NIH – National Heart, Lung, and Blood Institute)
U54HG006504 (NIH – National Human Genome Research Institute)
Publication Type:
Article
Unique ID:
10.1161/CIRCRESAHA.120.317107
PMID:
34886679
DOI:
10.1161/CIRCRESAHA.120.317107
Journal:
Circulation Research
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View Web of Science Record
View PubMed Record

Record Created:

Association of Damaging Variants in Genes with Increased Cancer Risk among Patients with Congenital Heart Disease

Morton, S. U., Shimamura, A., Newburger, P. E., Opotowsky, A. R., Quiat, D., Pereira, A. C., Jin, S. C., Gurvitz, M., Brueckner, M., Chung, W. K., Shen, Y., Bernstein, D., Gelb, B. D., Giardini, A., Goldmuntz, E., Kim, R. W., Lifton, R. P., Porter, G. A., Srivastava, D., … Seidman, C. E. (2021). Association of Damaging Variants in Genes With Increased Cancer Risk Among Patients With Congenital Heart Disease. JAMA Cardiology, 6(4), 457. https://doi.org/10.1001/jamacardio.2020.4947
Authors:
Christine E. Seidman
Sarah U. Morton
Akiko Shimamura
Peter E. Newburger
Alexander R. Opotowsky
Daniel Quiat
Alexandre C. Pereira
Sheng Chih Jin
Michelle Gurvitz
Martina Brueckner
Wendy K. Chung
Yufeng Shen
Daniel Bernstein
Bruce D. Gelb
Alessandro Giardini
Elizabeth Goldmuntz
Richard W. Kim
Richard P. Lifton
George A. Porter
Deepak Srivastava
Martin Tristani-Firouzi
Jane W. Newburger
J.G. Seidman
Affiliated Authors:
Wendy K. Chung
Yufeng Shen
Columbia Affiliation:
Subjects:
Genetic Predisposition to Disease (MeSH)
Heart Defects, Congenital (MeSH)
Neoplasms (MeSH)
Grants:
UL1TR000003 (NIH – National Center for Advancing Translational Sciences)
UL1TR001863 (NIH – National Center for Advancing Translational Sciences)
K99HL143036 (NIH – National Heart, Lung, and Blood Institute)
U01HL098162 (NIH – National Heart, Lung, and Blood Institute)
R00HL143036 (NIH – National Heart, Lung, and Blood Institute)
U01HL098188 (NIH – National Heart, Lung, and Blood Institute)
U01HL098123 (NIH – National Heart, Lung, and Blood Institute)
U01HL098147 (NIH – National Heart, Lung, and Blood Institute)
UM1HL128761 (NIH – National Heart, Lung, and Blood Institute)
U01HL098153 (NIH – National Heart, Lung, and Blood Institute)
R01HL057181 (NIH – National Heart, Lung, and Blood Institute)
U01HL153009 (NIH – National Heart, Lung, and Blood Institute)
R01GM120609 (NIH – National Institute of General Medical Sciences)
Publication Type:
Article
Unique ID:
10.1001/jamacardio.2020.4947
PMID:
33084842
DOI:
10.1001/jamacardio.2020.4947
Journal:
JAMA Cardiology
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View PubMed Record

Record Created:

CSV