U01AI178772

NIH – National Institute of Allergy and Infectious Diseases

Clinical and molecular analysis of longitudinal rhinitis phenotypes in an urban birth cohort

Ramratnam, S. K., Johnson, M., Visness, C. M., Calatroni, A., Altman, M. C., Janczyk, T., McCauley, K. E., Schachtschneider, C., Fujimura, K. E., Fadrosh, D. W., Lynch, S. V., Bacharier, L. B., O’Connor, G. T., Sandel, M. T., Kattan, M., Wood, R. A., Gergen, P. J., Jackson, D. J., Togias, A., & Gern, J. E. (2024). Clinical and molecular analysis of longitudinal rhinitis phenotypes in an urban birth cohort. Journal of Allergy and Clinical Immunology. https://doi.org/10.1016/j.jaci.2024.08.031

Authors:

Sima K Ramratnam

Molly Johnson

Cynthia M Visness

Agustin Calatroni

Mathew C Altman

Tomasz Janczyk

Kathryn E McCauley

Claire Schachtschneider

Kei E Fujimura

Douglas W Fadrosh

Susan V Lynch

Leonard B Bacharier

George T O'Connor

Megan T Sandel

Meyer Kattan

Robert A Wood

Peter J Gergen

Daniel J Jackson

Alkis Togias

James E Gern

Affiliated Authors:

Meyer Kattan

Columbia Affiliation:

Vagelos College of Physicians and Surgeons
- Department of Pediatrics
  Division of Pediatric Pulmonology

Author Keywords:

allergic sensitization

chronic rhinitis

endotypes

environmental exposures

hay fever

phenotypes

seasonal rhinitis

transcriptomics

immunoglobulin e

allergens

allergen

antibiotic agent

biological marker

endotoxin

transcriptome

adaptive immunity

airway

allergic disease

allergic rhinitis

article

asthma

birth cohort

child

common cold

comorbidity

controlled study

corynebacterium

differential gene expression

environmental exposure

eosinophil

faecalibacterium

family structure

female

gene expression

genetic profile

house dust

human

immune response gene

infant

lachnospiraceae

lactobacillus

longitudinal study

major clinical study

male

nasal epithelial cell

newborn

phenotype

postnatal depression

risk factor

rna sequencing

sensitization

temporal analysis

urban area

chronic disease

epidemiology

genetics

immunology

nose mucosa

preschool child

rhinitis

urban population

child, preschool

humans

longitudinal studies

nasal mucosa

risk factors

Grants:

UL1TR001430 (NIH – National Center for Advancing Translational Sciences)

U01AI178772 (NIH – National Institute of Allergy and Infectious Diseases)

UM2AI117870 (NIH – National Institute of Allergy and Infectious Diseases)

Publication Type:

Article

Unique ID:

10.1016/j.jaci.2024.08.031

PMID:

39307288

DOI:

10.1016/j.jaci.2024.08.031

Journal:

Journal of Allergy and Clinical Immunology

Publication Date:

2024-09-23

Data Source:

PubMed

Source Link:

View PubMed Record

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Record Created:

Thursday, December 5, 2024 - 09:26

Viral and non-viral episodes of wheezing in early life and the development of asthma and respiratory phenotypes among urban children

Havens, T. N., LeBeau, P., Calatroni, A., Gern, J. E., O’Connor, G. T., Wood, R. A., Lamm, C., Krouse, R. Z., Visness, C. M., Gergen, P. J., Jackson, D. J., & Bacharier, L. B. (2024). Viral and non‐viral episodes of wheezing in early life and the development of asthma and respiratory phenotypes among urban children. Pediatric Allergy and Immunology, 35(7). Portico. https://doi.org/10.1111/pai.14197

Authors:

Tara N Havens

Petra LeBeau

Agustin Calatroni

James E Gern

George T O'Connor

Robert A Wood

Carin Lamm

Rebecca Z Krouse

Cynthia M Visness

Peter J Gergen

Daniel J Jackson

Leonard B Bacharier

Affiliated Authors:

Carin Lamm

Columbia Affiliation:

Vagelos College of Physicians and Surgeons
- Department of Pediatrics
  Division of Pediatric Pulmonology

Subjects:

Respiratory Sounds (MeSH)

Asthma (MeSH)

Phenotype (MeSH)

Urban Population (MeSH)

Author Keywords:

asthma

children

phenotypes

viral

wheeze

Grants:

K23RR016070 (NIH – National Center for Research Resources)

M01RR000052 (NIH – National Center for Research Resources)

M01RR000071 (NIH – National Center for Research Resources)

M01RR000533 (NIH – National Center for Research Resources)

M01RR002719 (NIH – National Center for Research Resources)

N01AI025496 (NIH – National Institute of Allergy and Infectious Diseases)

U01AI178772 (NIH – National Institute of Allergy and Infectious Diseases)

UL1RR024156 (NIH – National Center for Research Resources)

UL1RR024992 (NIH – National Center for Research Resources)

UL1RR025771 (NIH – National Center for Research Resources)

UL1TR000040 (NIH – National Center for Advancing Translational Sciences)

UL1TR001079 (NIH – National Center for Advancing Translational Sciences)

UM1AI114271 (NIH – National Institute of Allergy and Infectious Diseases)

UM1AI160040 (NIH – National Institute of Allergy and Infectious Diseases)

UM2AI117870 (NIH – National Institute of Allergy and Infectious Diseases)

Publication Type:

Article

Unique ID:

10.1111/pai.14197

PMID:

39016335

DOI:

10.1111/pai.14197

Journal:

Pediatric Allergy and Immunology

Publication Date:

2024-07-17

Data Source:

PubMed

Source Link:

View PubMed Record

Record Created:

Wednesday, September 24, 2025 - 12:33

Relationships between lung function, allergy, and wheezing in urban children

Konno-Yamamoto, A., Goswamy, V., Calatroni, A., Gergen, P. J., Johnson, M., Sorkness, R. L., Bacharier, L. B., O’Connor, G. T., Kattan, M., Wood, R. A., Gagalis, L., Visness, C. M., & Gern, J. E. (2024). Relationships between lung function, allergy, and wheezing in urban children. Journal of Allergy and Clinical Immunology, 154(2), 316-324.e3. https://doi.org/10.1016/j.jaci.2024.02.025

Authors:

Aya Konno-Yamamoto

Vinay Goswamy

Agustin Calatroni

Peter J Gergen

Molly Johnson

Ronald L Sorkness

Leonard B Bacharier

George T O'Connor

Meyer Kattan

Robert A Wood

Lisa Gagalis

Cynthia M Visness

James E Gern

Affiliated Authors:

Meyer Kattan

Columbia Affiliation:

Vagelos College of Physicians and Surgeons
- Department of Pediatrics
  Division of Pediatric Pulmonology

Subjects:

Respiratory Sounds (MeSH)

Urban Population (MeSH)

Lung (MeSH)

Author Keywords:

childhood asthma

allergic sensitization

impulse oscillometry

lung function

spirometry

Grants:

K23RR016070 (NIH – National Center for Research Resources)

M01RR000052 (NIH – National Center for Research Resources)

M01RR000071 (NIH – National Center for Research Resources)

M01RR000533 (NIH – National Center for Research Resources)

M01RR002719 (NIH – National Center for Research Resources)

N01AI025496 (NIH – National Institute of Allergy and Infectious Diseases)

U01AI178772 (NIH – National Institute of Allergy and Infectious Diseases)

UL1RR024156 (NIH – National Center for Research Resources)

UL1RR024992 (NIH – National Center for Research Resources)

UL1RR025771 (NIH – National Center for Research Resources)

UL1TR000040 (NIH – National Center for Advancing Translational Sciences)

UL1TR001079 (NIH – National Center for Advancing Translational Sciences)

UL1TR001430 (NIH – National Center for Advancing Translational Sciences)

UL1TR001873 (NIH – National Center for Advancing Translational Sciences)

UL1TR002345 (NIH – National Center for Advancing Translational Sciences)

UM1AI114271 (NIH – National Institute of Allergy and Infectious Diseases)

UM1AI160040 (NIH – National Institute of Allergy and Infectious Diseases)

UM2AI117870 (NIH – National Institute of Allergy and Infectious Diseases)

Publication Type:

Article

Unique ID:

10.1016/j.jaci.2024.02.025

PMID:

38574825

DOI:

10.1016/j.jaci.2024.02.025

Journal:

Journal of Allergy and Clinical Immunology

Publication Date:

2024-04-05

Data Source:

PubMed

Source Link:

View PubMed Record

Record Created:

Wednesday, September 24, 2025 - 12:33

Early-life nasal microbiota dynamics relate to longitudinal respiratory phenotypes in urban children

McCauley, K. E., Durack, J., Lynch, K. V., Fadrosh, D. W., Fujimura, K. E., Vundla, F., Özçam, M., LeBeau, P., Caltroni, A., Burns, P., Tran, H. T., Bacharier, L. B., Kattan, M., O’Connor, G. T., Wood, R. A., Togias, A., Boushey, H. A., Jackson, D. J., Gern, J. E., & Lynch, S. V. (2024). Early-life nasal microbiota dynamics relate to longitudinal respiratory phenotypes in urban children. Journal of Allergy and Clinical Immunology, 153(6), 1563–1573. https://doi.org/10.1016/j.jaci.2023.12.032

Authors:

Kathryn E McCauley

Juliana Durack

Kole V Lynch

Douglas W Fadrosh

Kei E Fujimura

Faith Vundla

Mustafa Özçam

Petra LeBeau

Agustin Caltroni

Preston Burns

Hoang T Tran

Leonard B Bacharier

Meyer Kattan

George T O'Connor

Robert A Wood

Alkis Togias

Homer A Boushey

Daniel J Jackson

James E Gern

Susan V Lynch

Affiliated Authors:

Meyer Kattan

Columbia Affiliation:

Vagelos College of Physicians and Surgeons
- Department of Pediatrics
  Division of Pediatric Pulmonology

Subjects:

Microbiota (MeSH)

Phenotype (MeSH)

Urban Population (MeSH)

Respiratory Sounds (MeSH)

Author Keywords:

asthma

airway microbiota

atopy

early childhood

respiratory phenotypes

Grants:

T32DK007762 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)

K23RR016070 (NIH – National Center for Research Resources)

M01RR000052 (NIH – National Center for Research Resources)

M01RR000071 (NIH – National Center for Research Resources)

M01RR000533 (NIH – National Center for Research Resources)

M01RR002719 (NIH – National Center for Research Resources)

U01AI178772 (NIH – National Institute of Allergy and Infectious Diseases)

UG3OD023282 (NIH – Office of the Director, National Institutes of Health)

UH3OD023282 (NIH – Office of the Director, National Institutes of Health)

UL1RR024156 (NIH – National Center for Research Resources)

UL1RR024992 (NIH – National Center for Research Resources)

UL1RR025771 (NIH – National Center for Research Resources)

UL1TR000040 (NIH – National Center for Advancing Translational Sciences)

UL1TR001079 (NIH – National Center for Advancing Translational Sciences)

UL1TR001873 (NIH – National Center for Advancing Translational Sciences)

UL1TR002345 (NIH – National Center for Advancing Translational Sciences)

UM1AI160040 (NIH – National Institute of Allergy and Infectious Diseases)

Publication Type:

Article

Unique ID:

10.1016/j.jaci.2023.12.032

PMID:

38423369

DOI:

10.1016/j.jaci.2023.12.032

Journal:

Journal of Allergy and Clinical Immunology

Publication Date:

2024-03-01

Data Source:

PubMed

Source Link:

View PubMed Record

Record Created:

Wednesday, September 24, 2025 - 12:33