R21MH119803

NIH – National Institute of Mental Health

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Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1

Tejwani, L., Ravindra, N. G., Lee, C., Cheng, Y., Nguyen, B., Luttik, K., Ni, L., Zhang, S., Morrison, L. M., Gionco, J., Xiang, Y., Yoon, J., Ro, H., Haidery, F., Grijalva, R. M., Bae, E., Kim, K., Martuscello, R. T., Orr, H. T., … Lim, J. (2024). Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1. Neuron, 112(3), 362-383.e15. https://doi.org/10.1016/j.neuron.2023.10.039
Authors:
Leon Tejwani
Neal G Ravindra
Changwoo Lee
Yubao Cheng
Billy Nguyen
Kimberly Luttik
Luhan Ni
Shupei Zhang
Logan M Morrison
John Gionco
Yangfei Xiang
Jennifer Yoon
Hannah Ro
Fatema Haidery
Rosalie M Grijalva
Eunwoo Bae
Kristen Kim
Regina T Martuscello
Harry T Orr
Huda Y Zoghbi
Hayley S McLoughlin
Laura P W Ranum
Vikram G Shakkottai
Phyllis L Faust
Siyuan Wang
David van Dijk
Janghoo Lim
Affiliated Authors:
John Gionco
Regina T Martuscello
Phyllis L Faust
Columbia Affiliation:
Subjects:
Spinocerebellar Ataxias (MeSH)
Author Keywords:
ataxin-1
machine learning
neurodegeneration
oligodendrocyte
oligodendrocyte progenitor cell
purkinje cell
sca1
single-nucleus rna sequencing
spinocerebellar ataxia type 1
unipolar brush cells
Grants:
R01HG011245 (NIH – National Human Genome Research Institute)
R21MH119803 (NIH – National Institute of Mental Health)
R01NS083706 (NIH – National Institute of Neurological Disorders and Stroke)
T32NS007224 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS085054 (NIH – National Institute of Neurological Disorders and Stroke)
T32NS041228 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS027699 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS088321 (NIH – National Institute of Neurological Disorders and Stroke)
P30AG053760 (NIH – National Institute On Aging)
R01AG076154 (NIH – National Institute On Aging)
R01AG066447 (NIH – National Institute On Aging)
R01AG074609 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1016/j.neuron.2023.10.039
PMID:
38016472
DOI:
10.1016/j.neuron.2023.10.039
Journal:
Neuron
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record
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Record Created:

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