DLBCL-associated NOTCH2 mutations escape ubiquitin-dependent degradation and promote chemoresistance
Zhou, N., Choi, J., Grothusen, G., Kim, B.-J., Ren, D., Cao, Z., Liu, Y., Li, Q., Inamdar, A., Beer, T., Tang, H.-Y., Perkey, E., Maillard, I., Bonasio, R., Shi, J., Ruella, M., Wan, L., & Busino, L. (2023). DLBCL-associated NOTCH2 mutations escape ubiquitin-dependent degradation and promote chemoresistance. Blood, 142(11), 973–988. https://doi.org/10.1182/blood.2022018752
Columbia Affiliation:
Subjects:
Drug Resistance, Neoplasm
(MeSH)
Ubiquitin-Proteasome Proteolytic Pathway
(OpenAlex Topic)
Targeted Protein Degradation in Biomedical Research
(OpenAlex Topic)
Lymphoid Neoplasms
(OpenAlex Topic)
Grants:
R50CA221838
(NIH – National Cancer Institute)
R37CA262362
(NIH – National Cancer Institute)
R01CA207513
(NIH – National Cancer Institute)
R00CA226399
(NIH – National Cancer Institute)
P30CA010815
(NIH – National Cancer Institute)
P01CA214278
(NIH – National Cancer Institute)
DP2HG012443
(NIH – National Human Genome Research Institute)
R01AI091627
(NIH – National Institute of Allergy and Infectious Diseases)
Publication Type:
Article
Unique ID:
10.1182/blood.2022018752
PMID:
Journal:
Publication Date:
Data Source:
OpenAlex
Source Link: