Hedgehog Proteins

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Chung, K. M., Kim, H., Roque, C. G., McCurdy, E. P., Nguyen, T. T. T., Siegelin, M. D., Hwang, J.-Y., & Hengst, U. (2022). A systemic cell stress signal confers neuronal resilience toward oxidative stress in a Hedgehog-dependent manner. Cell Reports, 41(3), 111488. https://doi.org/10.1016/j.celrep.2022.111488
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Scales, M. K., Velez-Delgado, A., Steele, N. G., Schrader, H. E., Stabnick, A. M., Yan, W., Mercado Soto, N. M., Nwosu, Z. C., Johnson, C., Zhang, Y., Salas-Escabillas, D. J., Menjivar, R. E., Maurer, H. C., Crawford, H. C., Bednar, F., Olive, K. P., Pasca di Magliano, M., & Allen, B. L. (2022). Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer. PLOS Genetics, 18(7), e1010315. https://doi.org/10.1371/journal.pgen.1010315
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Gounder, M. M., Rosenbaum, E., Wu, N., Dickson, M. A., Sheikh, T. N., D’Angelo, S. P., Chi, P., Keohan, M. L., Erinjeri, J. P., Antonescu, C. R., Agaram, N., Hameed, M. R., Martindale, M., Lefkowitz, R. A., Crago, A. M., Singer, S., Tap, W. D., Takebe, N., Qin, L.-X., & Schwartz, G. K. (2022). A Phase Ib/II Randomized Study of RO4929097, a Gamma-Secretase or Notch Inhibitor with or without Vismodegib, a Hedgehog Inhibitor, in Advanced Sarcoma. Clinical Cancer Research, 28(8), 1586–1594. https://doi.org/10.1158/1078-0432.ccr-21-3874
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