Loss of Heterozygosity

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Lin, A. L., Rudneva, V. A., Richards, A. L., Zhang, Y., Woo, H. J., Cohen, M., Tisnado, J., Majd, N., Wardlaw, S. L., Page-Wilson, G., Sengupta, S., Chow, F., Goichot, B., Ozer, B. H., Dietrich, J., Nachtigall, L., Desai, A., Alano, T., Ogilive, S., … Tabar, V. (2024). Genome-wide loss of heterozygosity predicts aggressive, treatment-refractory behavior in pituitary neuroendocrine tumors. Acta Neuropathologica, 147(1). https://doi.org/10.1007/s00401-024-02736-8
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Yan, H., Yu, C.-C., Fine, S. A., Youssof, A. L., Yang, Y.-R., Yan, J., Karg, D. C., Cheung, E. C., Friedman, R. A., Ying, H., Chen, E. I., Luo, J., Miao, Y., Qiu, W., & Su, G. H. (2021). Loss of the wild-type KRAS allele promotes pancreatic cancer progression through functional activation of YAP1. Oncogene, 40(50), 6759–6771. https://doi.org/10.1038/s41388-021-02040-9
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Abbass, M. A., Leach, B., & Church, J. M. (2021). The Second Allele: A Key to Understanding the Timing of Sporadic and Hereditary Colorectal Tumorigenesis. Genes, 12(10), 1515. https://doi.org/10.3390/genes12101515
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He, Y., Rivera, J., Diossy, M., Duan, H., Bowman-Colin, C., Reed, R., Jennings, R., Novak, J., Tran, S. V., Cohen, E. F., Szuts, D., Giobbie-Hurder, A., Bronson, R. T., Bass, A. J., Signoretti, S., Szallasi, Z., Livingston, D. M., & Pathania, S. (2021). BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model. Proceedings of the National Academy of Sciences, 118(41). https://doi.org/10.1073/pnas.2108421118
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