Phospholipids

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Sassano, M. L., Tyurina, Y. Y., Diometzidou, A., Vervoort, E., Tyurin, V. A., More, S., La Rovere, R., Giordano, F., Bultynck, G., Pavie, B., Swinnen, J. V., Bayir, H., Kagan, V. E., Scorrano, L., & Agostinis, P. (2025). Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis. Nature Cell Biology, 27(6), 902–917. https://doi.org/10.1038/s41556-025-01668-z
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Suber, T. L., Tabary, M., Bain, W., Olonisakin, T., Lockwood, K., Xiong, Z., Zhang, Y., Kohli, N., Furguiele, L., Peñaloza, H., McVerry, B. J., Rose, J. J., Shah, F., Methé, B., Li, K., Mallampalli, R. K., Chen, K., Fan, L., Morris, A., … Lee, J. S. (2024). Oxidized phospholipid and transcriptomic signatures of THC-related vaping associated lung injury. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-79585-8
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Qiu, B., Zandkarimi, F., Bezjian, C. T., Reznik, E., Soni, R. K., Gu, W., Jiang, X., & Stockwell, B. R. (2024). Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosis. Cell, 187(5), 1177-1190.e18. https://doi.org/10.1016/j.cell.2024.01.030
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Murari, A., Rhooms, S.-K., Vimal, D., Hossain, K. F. B., Saini, S., Villanueva, M., Schlame, M., & Owusu-Ansah, E. (2023). Phospholipids can regulate complex I assembly independent of their role in maintaining mitochondrial membrane integrity. Cell Reports, 42(8), 112846. https://doi.org/10.1016/j.celrep.2023.112846
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Dou, H., Kotini, A., Liu, W., Fidler, T., Endo-Umeda, K., Sun, X., Olszewska, M., Xiao, T., Abramowicz, S., Yalcinkaya, M., Hardaway, B., Tsimikas, S., Que, X., Bick, A., Emdin, C., Natarajan, P., Papapetrou, E. P., Witztum, J. L., Wang, N., & Tall, A. R. (2021). Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency. Circulation, 144(24), 1940–1954. https://doi.org/10.1161/circulationaha.121.056414
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Li, J., Han, L., Vallese, F., Ding, Z., Choi, S. K., Hong, S., Luo, Y., Liu, B., Chan, C. K., Tajkhorshid, E., Zhu, J., Clarke, O., Zhang, K., & Gennis, R. (2021). Cryo-EM structures of Escherichia coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site. Proceedings of the National Academy of Sciences, 118(34). https://doi.org/10.1073/pnas.2106750118
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