Symporters

Subject Vocabulary
MeSH
Unique ID
D027981

Joint host-pathogen genomic analysis identifies hepatitis B virus mutations associated with human NTCP and HLA class I variation

Xu, Z. M., Gnouamozi, G. E., Rüeger, S., Shea, P. R., Buti, M., Chan, H. LY., Marcellin, P., Lawless, D., Naret, O., Zeller, M., Schneuing, A., Scheck, A., Junier, T., Moradpour, D., Podlaha, O., Suri, V., Gaggar, A., Subramanian, M., Correia, B., … Fellay, J. (2024). Joint host-pathogen genomic analysis identifies hepatitis B virus mutations associated with human NTCP and HLA class I variation. The American Journal of Human Genetics, 111(6), 1018–1034. https://doi.org/10.1016/j.ajhg.2024.04.013
Authors:
Zhi Ming Xu
Gnimah Eva Gnouamozi
Sina Rüeger
Patrick R Shea
Maria Buti
Henry Ly Chan
Patrick Marcellin
Dylan Lawless
Olivier Naret
Matthias Zeller
Arne Schneuing
Andreas Scheck
Thomas Junier
Darius Moradpour
Ondrej Podlaha
Vithika Suri
Anuj Gaggar
Mani Subramanian
Bruno Correia
David Gfeller
Stephan Urban
Jacques Fellay
Affiliated Authors:
Patrick R Shea
Columbia Affiliation:
Subjects:
Hepatitis B virus (MeSH)
Organic Anion Transporters, Sodium-Dependent (MeSH)
Symporters (MeSH)
Mutation (MeSH)
Author Keywords:
hbv entry
escape variants
evolutionary genomics
hepatitis b virus
host-pathogen genomics
immunogenetics
selection
viral restriction
Publication Type:
Article
Unique ID:
10.1016/j.ajhg.2024.04.013
PMID:
38749427
DOI:
10.1016/j.ajhg.2024.04.013
Journal:
American Journal of Human Genetics
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

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Substrate binding-induced conformational transitions in the omega-3 fatty acid transporter MFSD2A

Bergman, S., Cater, R. J., Plante, A., Mancia, F., & Khelashvili, G. (2023). Substrate binding-induced conformational transitions in the omega-3 fatty acid transporter MFSD2A. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-39088-y
Authors:
Shana Bergman
Rosemary J Cater
Ambrose Plante
Filippo Mancia
George Khelashvili
Affiliated Authors:
Rosemary J Cater
Filippo Mancia
Columbia Affiliation:
Subjects:
Fatty Acids, Omega-3 (MeSH)
Symporters (MeSH)
Grants:
R21MH125649 (NIH – National Institute of Mental Health)
T32DA039080 (NIH – National Institute On Drug Abuse)
Publication Type:
Article
Unique ID:
10.1038/s41467-023-39088-y
PMID:
37296098
DOI:
10.1038/s41467-023-39088-y
Journal:
Nature Communications
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

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Structural insights into the mechanism of the sodium/iodide symporter

Ravera, S., Nicola, J. P., Salazar-De Simone, G., Sigworth, F. J., Karakas, E., Amzel, L. M., Bianchet, M. A., & Carrasco, N. (2022). Structural insights into the mechanism of the sodium/iodide symporter. Nature, 612(7941), 795–801. https://doi.org/10.1038/s41586-022-05530-2
Authors:
Silvia Ravera
Juan Pablo Nicola
Glicella Salazar-De Simone
Fred J Sigworth
Erkan Karakas
L Mario Amzel
Mario A Bianchet
Nancy Carrasco
Affiliated Authors:
Glicella Salazar-De Simone
Columbia Affiliation:
Subjects:
Iodides (MeSH)
Sodium (MeSH)
Symporters (MeSH)
Grants:
R01GM114250 (NIH – National Institute of General Medical Sciences)
Publication Type:
Article
Unique ID:
10.1038/s41586-022-05530-2
PMID:
36517601
DOI:
10.1038/s41586-022-05530-2
Journal:
Nature
Publication Date:
Data Source:
PubMed
Source Link:
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Rare pathogenic variants in WNK3 cause X-linked intellectual disability

Küry, S., Zhang, J., Besnard, T., Caro-Llopis, A., Zeng, X., Robert, S. M., Josiah, S. S., Kiziltug, E., Denommé-Pichon, A.-S., Cogné, B., Kundishora, A. J., Hao, L. T., Li, H., Stevenson, R. E., Louie, R. J., Deb, W., Torti, E., Vignard, V., McWalter, K., … Isidor, B. (2022). Rare pathogenic variants in WNK3 cause X-linked intellectual disability. Genetics in Medicine, 24(9), 1941–1951. https://doi.org/10.1016/j.gim.2022.05.009
Authors:
Sébastien Küry
Jinwei Zhang
Thomas Besnard
Alfonso Caro-Llopis
Xue Zeng
Stephanie M Robert
Sunday S Josiah
Emre Kiziltug
Anne-Sophie Denommé-Pichon
Benjamin Cogné
Adam J Kundishora
Le T Hao
Hong Li
Roger E Stevenson
Raymond J Louie
Wallid Deb
Erin Torti
Virginie Vignard
Kirsty McWalter
F Lucy Raymond
Farrah Rajabi
Emmanuelle Ranza
Detelina Grozeva
Stephanie A Coury
Xavier Blanc
Elise Brischoux-Boucher
Boris Keren
Katrin Õunap
Karit Reinson
Pilvi Ilves
Ingrid M Wentzensen
Eileen E Barr
Solveig Heide Guihard
Perrine Charles
Eleanor G Seaby
Kristin G Monaghan
Marlène Rio
Yolande van Bever
Marjon van Slegtenhorst
Wendy K Chung
Ashley Wilson
Delphine Quinquis
Flora Bréhéret
Kyle Retterer
Pierre Lindenbaum
Emmanuel Scalais
Lindsay Rhodes
Katrien Stouffs
Elaine M Pereira
Sara M Berger
Sarah S Milla
Ankita B Jaykumar
Melanie H Cobb
Shreyas Panchagnula
Phan Q Duy
Marie Vincent
Sandra Mercier
Brigitte Gilbert-Dussardier
Xavier Le Guillou
Séverine Audebert-Bellanger
Sylvie Odent
Sébastien Schmitt
Pierre Boisseau
Dominique Bonneau
Annick Toutain
Estelle Colin
Laurent Pasquier
Richard Redon
Arjan Bouman
Jill A Rosenfeld
Michael J Friez
Helena Pérez-Peña
Syed Raza Akhtar Rizvi
Shozeb Haider
Stylianos E Antonarakis
Charles E Schwartz
Francisco Martínez
Stéphane Bézieau
Kristopher T Kahle
Bertrand Isidor
Affiliated Authors:
Wendy K Chung
Ashley Wilson
Elaine M Pereira
Sara M Berger
Columbia Affiliation:
Subjects:
Molecular Basis of Rett Syndrome and Related Disorders (OpenAlex Topic)
Molecular Mechanisms of Aquaporins in Physiology and Disease (OpenAlex Topic)
Standards and Guidelines for Genetic Variant Interpretation (OpenAlex Topic)
Mental Retardation, X-Linked (MeSH)
Protein Serine-Threonine Kinases (MeSH)
Symporters (MeSH)
Author Keywords:
exome sequencing
kcc2
neurodevelopmental disease
wnk3
x-linked intellectual disability
Grants:
UM1HG008900 (NIH – National Human Genome Research Institute)
R01NS073854 (NIH – National Institute of Neurological Disorders and Stroke)
Publication Type:
Article
Unique ID:
10.1016/j.gim.2022.05.009
PMID:
35678782
DOI:
10.1016/j.gim.2022.05.009
Journal:
Genetics in Medicine
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created:

Structural basis of omega-3 fatty acid transport across the blood–brain barrier

Cater, R. J., Chua, G. L., Erramilli, S. K., Keener, J. E., Choy, B. C., Tokarz, P., Chin, C. F., Quek, D. Q. Y., Kloss, B., Pepe, J. G., Parisi, G., Wong, B. H., Clarke, O. B., Marty, M. T., Kossiakoff, A. A., Khelashvili, G., Silver, D. L., & Mancia, F. (2021). Structural basis of omega-3 fatty acid transport across the blood–brain barrier. Nature, 595(7866), 315–319. https://doi.org/10.1038/s41586-021-03650-9
Authors:
Rosemary J. Cater
Geok Lin Chua
Satchal K. Erramilli
James E. Keener
Brendon C. Choy
Piotr Tokarz
Cheen Fei Chin
Debra Q. Y. Quek
Brian Kloss
Joseph G. Pepe
Giacomo Parisi
Bernice H. Wong
Oliver B. Clarke
Michael T. Marty
Anthony A. Kossiakoff
George Khelashvili
David L. Silver
Filippo Mancia
Affiliated Authors:
Rosemary J. Cater
Brendon C. Choy
Joseph G. Pepe
Giacomo Parisi
Oliver B. Clarke
Filippo Mancia
Columbia Affiliation:
Subjects:
Biological Transport (MeSH)
Blood-Brain Barrier (MeSH)
Cryoelectron Microscopy (MeSH)
Fatty Acids, Omega-3 (MeSH)
Symporters (MeSH)
Grants:
R01GM117372 (NIH – National Institute of General Medical Sciences)
R35GM132120 (NIH – National Institute of General Medical Sciences)
R35GM128624 (NIH – National Institute of General Medical Sciences)
R21MH125649 (NIH – National Institute of Mental Health)
Publication Type:
Article
Unique ID:
10.1038/s41586-021-03650-9
PMID:
34135507
DOI:
10.1038/s41586-021-03650-9
Journal:
Nature
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View PubMed Record
View Web of Science Record

Record Created:

CSV