Advancements in Lung Cancer Research

Displaying 1 - 36 of 36CSV
Jurkiewicz, M., Yeh, R., Shu, C. A., Hsiao, S. J., Mansukhani, M. M., Saqi, A., & Fernandes, H. (2025). Challenges in Amplicon-Based DNA NGS Identification of MET Exon 14 Skipping Events in Non-Small Cell Lung Cancers. Journal of Molecular Pathology, 6(1), 5. https://doi.org/10.3390/jmp6010005
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Marks, L. J., Ritter, V., Agrusa, J., Kamdar, K. Y., Rivers, J., Gardner, R. A., Ehrhardt, M. J., Devine, K. J., Phillips, C. A., Reilly, A. F., August, K., Weinstein, J. L., Satwani, P., Forlenza, C. J., Smith, C. M., Greer, C., Afify, Z., Lin, C. H., Belsky, J. A., … Aftandilian, C. (2025). Pediatric relapsed/refractory ALK+ anaplastic large cell lymphoma treatment and outcomes in the targeted drug era. Blood Advances. https://doi.org/10.1182/bloodadvances.2024014745
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Henick, B. S., Koch, P. D., Gainor, J. F., Awad, M. M., Chiuzan, C., Izard, S., Georgis, Y., Mallick, S., Garofano, R. F., Wong, C. V., Saqi, A., Grindheim, J., Schulze, K., Sonett, J. R., Rizvi, N. A., Izar, B., Taylor, A. M., & Shu, C. A. (2024). Neoadjuvant atezolizumab + chemotherapy for resectable NSCLC: 3-year clinical update of phase II clinical trial results and translational findings. Journal for ImmunoTherapy of Cancer, 12(12), e009301. https://doi.org/10.1136/jitc-2024-009301
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Mallick, S., Henick, B., Georgis, Y., Zhakula, N., Concepcion-Crisol, C., Herzberg, B., & Taylor, A. (2024). 1365 Chromosome 19p status associates with clinical outcomes in a histology-dependent manner in non-small cell lung cancer. Regular and Young Investigator Award Abstracts, A1529–A1529. https://doi.org/10.1136/jitc-2024-sitc2024.1365
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Spira, A., Girard, N., Krebs, M., Park, K., Shu, C., Dougherty, L., & Cho, B. C. (2023). A plain language summary of the results from the group of patients in the CHRYSALIS study with EGFR exon 20 insertion-mutated non-small-cell lung cancer who received amivantamab. Future Oncology, 19(33), 2213–2225. https://doi.org/10.2217/fon-2023-0284
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Shuryak, I., Wang, E., & Brenner, D. J. (2024). Understanding the impact of radiotherapy fractionation on overall survival in a large head and neck squamous cell carcinoma dataset: a comprehensive approach combining mechanistic and machine learning models. Frontiers in Oncology, 14. https://doi.org/10.3389/fonc.2024.1422211
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Mazul, A. L., Barrett, T. F., Colditz, G., Parikh, A. S., Ramadan, S., Zevallos, J. P., Rich, J. T., Harbison, R. A., Jackson, R. S., Pipkorn, P., Zolkind, P., Tirosh, I., & Puram, S. V. (2024). A hybrid epithelial/mesenchymal state in head and neck cancer: A biomarker for survival with differential prognosis by self-reported race. Med, 5(7), 826-831.e3. https://doi.org/10.1016/j.medj.2024.05.014
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Madarang, E., Lykon, J., Zhao, W., Sekeres, M. A., Bradley, T., Chandhok, N. S., Taylor, J., Venugopal, S., Koru-Sengul, T., Iyer, S. G., Gilbert, J. S., Miller, R. M., Nanni, J., Zacheo, I., Mattei, A., Al Ali, N., Kishtagari, A., Marconi, G., Sallman, D. A., … Watts, J. (2024). Venetoclax and hypomethylating agents in octogenarians and nonagenarians with acute myeloid leukemia. Blood Neoplasia, 1(2), 100016. https://doi.org/10.1016/j.bneo.2024.100016
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Chen, L. N., Stanifer, B. P., Sonett, J. R., & Shu, C. A. (2024). Advancing neoadjuvant immunotherapy in non-small cell lung cancer (NSCLC): commentary on the Lung Cancer Mutation Consortium 3 trial (LCMC3). AME Clinical Trials Review, 2, 37–37. https://doi.org/10.21037/actr-24-13
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Felip, E., Shu, C. A., Aguilar, A., Tang, K.-J., García Campelo, M. R., Lee, K.-Y., Delmonte, A., Sabari, J., Girard, N., Mansfield, A. S., Park, K., Zhou, C., Xia, K., Bhattacharya, A., Wade, M., Baig, M., Agrawal, T., Mahadevia, P., Knoblauch, R. E., & Sanborn, R. E. (2024). 2MO Amivantamab plus chemotherapy vs chemotherapy as first-line treatment in EGFR exon 20 insertion-mutated advanced NSCLC: Analysis of post-progression endpoints from PAPILLON. ESMO Open, 9, 102581. https://doi.org/10.1016/j.esmoop.2024.102581
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Wang, K., Du, R., Myall, N. J., Lewis, W. E., Uy, N., Hong, L., Skoulidis, F., Byers, L. A., Tsao, A., Cascone, T., Pozadzides, J., Tu, J., Negrao, M. V., Gibbons, D. L., Park, K., Rinsurongkawong, W., Lee, J. J., Gandara, D., Behl, D., … Le, X. (2024). Real-World Efficacy and Safety of Amivantamab for EGFR-Mutant NSCLC. Journal of Thoracic Oncology, 19(3), 500–506. https://doi.org/10.1016/j.jtho.2023.11.020
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Salvatore, M. M., Liu, Y., Peng, B., Hsu, H. Y., Saqi, A., Tsai, W.-Y., Leu, C.-S., & Jambawalikar, S. (2024). Comparison of lung cancer occurring in fibrotic versus non-fibrotic lung on chest CT. Journal of Translational Medicine, 22(1). https://doi.org/10.1186/s12967-023-04645-y
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Diaz, M., Chudsky, S., Pentsova, E., & Miller, A. M. (2024). Clinical applications of cerebrospinal fluid liquid biopsies in central nervous system tumors. Translational Oncology, 41, 101881. https://doi.org/10.1016/j.tranon.2024.101881
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Oxnard, G. R., Chen, R., Pharr, J. C., Koeller, D. R., Bertram, A. A., Dahlberg, S. E., Rainville, I., Shane-Carson, K., Taylor, K. A., Sable-Hunt, A., Sholl, L. M., Teerlink, C. C., Thomas, A., Cannon-Albright, L. A., Fay, A. P., Ashton-Prolla, P., Yang, H., Salvatore, M. M., Addario, B. J., … Garber, J. E. (2023). Germline EGFR Mutations and Familial Lung Cancer. Journal of Clinical Oncology, 41(34), 5274–5284. https://doi.org/10.1200/jco.23.01372
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Lee, J. M., Toloza, E. M., Pass, H. I., Johnson, B. E., Heymach, J. V., Sholl, L., Saqi, A., Travis, W. D., Wistuba, I., Lin, J., Kris, M. G., Spira, A. I., Shu, C. A., Saltos, A. N., Ding, B., Schulze, K., Zhu, Q., Ngiam, C., Bara, I., & Chaft, J. E. (2023). P2.01-06 NAUTIKA1 Study: Preliminary Efficacy and Safety Data with Neoadjuvant Alectinib in Patients with Stage IB-III ALK+ NSCLC. Journal of Thoracic Oncology, 18(11), S297–S298. https://doi.org/10.1016/j.jtho.2023.09.511
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Leighl, N., Cho, B. C., Hiret, S., Han, J.-Y., Lee, K. H., Llacer Perez, C., Krebs, M. G., De Braud, F., Haura, E., Sanborn, R. E., Yang, J. C.-H., Shu, C. A., Goto, K., Nishio, M., Zhao, J., Wang, Z., Tomasini, P., Felip, E., Goldman, J. W., … Spira, A. I. (2023). OA21.04 Amivantamab in Patients with Advanced NSCLC and MET Exon 14 Skipping Mutation: Results from the CHRYSALIS Study. Journal of Thoracic Oncology, 18(11), S93–S94. https://doi.org/10.1016/j.jtho.2023.09.105
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LaRose, M., Zhou, M., Lu, S., Wei, H., Bates, S. E., Schwartz, L., & Fojo, A. T. (2023). 1328P Analysis of data from the AENEAS study assessing the third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), aumolertinib, and virtual comparison with osimertinib. Annals of Oncology, 34, S766–S767. https://doi.org/10.1016/j.annonc.2023.09.2361
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Le, X., Patel, J., Shum, E., Sanborn, R. E., Baik, C. S., Shu, C. A., Kim, C., Fidler, M. D., Hall, R., Hanna, N., Mohindra, N., Sabari, J. K., Heeke, S., Hernandez, M., Gray, J. E., Heymach, J. V., & Saltos, A. (2023). LBA71 A multi-centre open-label randomized phase II study of osimertinib with and without ramucirumab in TKI-naïve EGFR-mutant metastatic NSCLC (RAMOSE trial interim analysis). Annals of Oncology, 34, S1313–S1314. https://doi.org/10.1016/j.annonc.2023.10.072
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Dacic, S., Travis, W., Redman, M., Saqi, A., Cooper, W. A., Borczuk, A., Chung, J.-H., Glass, C., Lopez, J. M., Roden, A. C., Sholl, L., Weissferdt, A., Posadas, J., Walker, A., Zhu, H., Wijeratne, M. T., Connolly, C., Wynes, M., Bota-Rabassedas, N., … Wistuba, I. (2023). International Association for the Study of Lung Cancer Study of Reproducibility in Assessment of Pathologic Response in Resected Lung Cancers After Neoadjuvant Therapy. Journal of Thoracic Oncology, 18(10), 1290–1302. https://doi.org/10.1016/j.jtho.2023.07.017
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Hijiya, N., Heneghan, M., Kapoor, S., Dhamal, V., Hoch, M., Descamps, L., Cardoso, A. P., & Pollard, J. (2023). POSTER: CML-532 ASC4KIDS: A Multicenter, Open-Label, Phase 1b/2 Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP). Clinical Lymphoma Myeloma and Leukemia, 23, S180. https://doi.org/10.1016/s2152-2650(23)00574-8
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Thummalapalli, R., Bernstein, E., Herzberg, B., Li, B. T., Iqbal, A., Preeshagul, I., Santini, F. C., Eng, J., Ladanyi, M., Yang, S.-R., Shen, R., Lito, P., Riely, G. J., Sabari, J. K., & Arbour, K. C. (2023). Clinical and Genomic Features of Response and Toxicity to Sotorasib in a Real-World Cohort of Patients With Advanced KRAS G12C-Mutant Non–Small Cell Lung Cancer. JCO Precision Oncology, 7. https://doi.org/10.1200/po.23.00030
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Kim, D.-W., Kim, S.-W., Camidge, D. R., Shu, C. A., Marrone, K. A., Le, X., Blakely, C. M., Park, K., Chang, G.-C., Patel, S. P., Kar, G., Cooper, Z. A., Samadani, R., Pluta, M., Kumar, R., & Ramalingam, S. (2023). CD73 Inhibitor Oleclumab Plus Osimertinib in Previously Treated Patients With Advanced T790M-Negative EGFR-Mutated NSCLC: A Brief Report. Journal of Thoracic Oncology, 18(5), 650–656. https://doi.org/10.1016/j.jtho.2022.12.021
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Ravi, A., Hellmann, M. D., Arniella, M. B., Holton, M., Freeman, S. S., Naranbhai, V., Stewart, C., Leshchiner, I., Kim, J., Akiyama, Y., Griffin, A. T., Vokes, N. I., Sakhi, M., Kamesan, V., Rizvi, H., Ricciuti, B., Forde, P. M., Anagnostou, V., Riess, J. W., … Gainor, J. F. (2023). Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer. Nature Genetics, 55(5), 807–819. https://doi.org/10.1038/s41588-023-01355-5
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Park, K., Sabari, J. K., Haura, E. B., Shu, C. A., Spira, A., Salgia, R., Reckamp, K. L., Sanborn, R. E., Govindan, R., Bauml, J. M., Curtin, J. C., Xie, J., Roshak, A., Lorenzini, P., Millington, D., Thayu, M., Knoblauch, R. E., & Cho, B. C. (2023). Management of infusion-related reactions (IRRs) in patients receiving amivantamab in the CHRYSALIS study. Lung Cancer, 178, 166–171. https://doi.org/10.1016/j.lungcan.2023.02.008
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de Castro, G., Rizvi, N. A., Schmid, P., Syrigos, K., Martin, C., Yamamoto, N., Cheng, Y., Moiseyenko, V., Summers, Y., Vynnychenko, I., Lee, S. Y., Bryl, M., Zer, A., Erman, M., Timcheva, C., Raja, R., Naicker, K., Scheuring, U., Walker, J., … Mok, T. (2023). NEPTUNE: Phase 3 Study of First-Line Durvalumab Plus Tremelimumab in Patients With Metastatic NSCLC. Journal of Thoracic Oncology, 18(1), 106–119. https://doi.org/10.1016/j.jtho.2022.09.223
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Savari, O., Febres‐Aldana, C., Chang, J. C., Fanaroff, R. E., Ventura, K., Bodd, F., Paik, P., Vundavalli, M., Saqi, A., Askin, F. B., Travis, W. D., & Rekhtman, N. (2022). Non‐small cell lung carcinomas with diffuse coexpression of TTF1 and p40: clinicopathological and genomic features of 14 rare biphenotypic tumours. Histopathology, 82(2), 242–253. Portico. https://doi.org/10.1111/his.14801
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Van Egeren, D., Kohli, K., Warner, J. L., Bedard, P. L., Riely, G., Lepisto, E., Schrag, D., LeNoue-Newton, M., Catalano, P., Kehl, K. L., Michor, F., Fiandalo, M., Foti, M., Khotskaya, Y., Lee, J., Peters, N., Sweeney, S., Abraham, J., … Walther, Z. (2022). Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-21448-1
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Pass, H., Kim, A. W., Felip, E., Shu, C. A., Ferris, A., Frueh, M., Gitlitz, B. J., Troutman, S., Petrek, H., Liu, X., Hsu, J., Patil, N., & Meng, R. D. (2022). 970TiP SKYSCRAPER-05: Phase II study of neoadjuvant atezolizumab (Atezo) + tiragolumab (Tira) with or without platinum-based chemotherapy (CT) in patients (Pts) with locally advanced resectable stage II‒IIIB NSCLC. Annals of Oncology, 33, S990–S991. https://doi.org/10.1016/j.annonc.2022.07.1096
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Ricciuti, B., Wang, X., Alessi, J. V., Rizvi, H., Mahadevan, N. R., Li, Y. Y., Polio, A., Lindsay, J., Umeton, R., Sinha, R., Vokes, N. I., Recondo, G., Lamberti, G., Lawrence, M., Vaz, V. R., Leonardi, G. C., Plodkowski, A. J., Gupta, H., Cherniack, A. D., … Awad, M. M. (2022). Association of High Tumor Mutation Burden in Non–Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels. JAMA Oncology, 8(8), 1160. https://doi.org/10.1001/jamaoncol.2022.1981
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Park, K., Sabari, J., Haura, E. B., Shu, C. A., Spira, A., Salgia, R., Reckamp, K. L., Sanborn, R. E., Govindan, R., Bauml, J. M., Curtin, J. C., Xie, J., Roshak, A., Lorenzini, P., Millington, D., Thayu, M., Knoblauch, R. E., & Cho, B. C. (2022). MO4-1 Management of infusion-related reactions in patients receiving amivantamab in the CHRYSALIS study. Annals of Oncology, 33, S482. https://doi.org/10.1016/j.annonc.2022.05.104
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Biswas, A. K., Han, S., Tai, Y., Ma, W., Coker, C., Quinn, S. A., Shakri, A. R., Zhong, T. J., Scholze, H., Lagos, G. G., Mela, A., Manova-Todorova, K., de Stanchina, E., Ferrando, A. A., Mendelsohn, C., Canoll, P., Yu, H. A., Paik, P. K., Saqi, A., … Acharyya, S. (2022). Targeting S100A9–ALDH1A1–Retinoic Acid Signaling to Suppress Brain Relapse inEGFR-Mutant Lung Cancer. Cancer Discovery, 12(4), 1002–1021. https://doi.org/10.1158/2159-8290.cd-21-0910
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Olazagasti, C., Ehrlich, M., Kohn, N., Aviles, K., Hoilett, A., & Seetharamu, N. (2022). Missed Opportunities? An Observational Analysis of Lung Cancer Screening Utilization Amongst Patients With Lung Cancer. Cancer Control, 29. https://doi.org/10.1177/10732748221077959
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