Biological and Clinical Effects of Ionizing Radiation

Displaying 1 - 24 of 24CSV
Ashrafi, A., Lin, Y., Fong, A. J., Islam, J. Y., Anderson, T. C. T., Ganesan, S., Heckman, C. J., & Llanos, A. A. M. (2025). Differences in COVID-19-Related Hospitalization, Treatment, Complications, and Death by Race and Ethnicity and Area-Level Measures Among Individuals with Cancer in the ASCO Registry. Cancers, 17(5), 857. https://doi.org/10.3390/cancers17050857
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Nemzow, L., Phillippi, M. A., Kanagaraj, K., Shuryak, I., Taveras, M., Wu, X., & Turner, H. C. (2024). Validation of a blood biomarker panel for machine learning-based radiation biodosimetry in juvenile and adult C57BL/6 mice. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-74953-w
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Royba, E., Shuryak, I., Ponnaiya, B., Repin, M., Pampou, S., Karan, C., Turner, H., Garty, G., & Brenner, D. J. (2024). Multiwell-based G0-PCC assay for radiation biodosimetry. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-69243-4
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Kanagaraj, K., Phillippi, M. A., Ober, E. H., Shuryak, I., Kleiman, N. J., Olson, J., Schaaf, G., Cline, J. M., & Turner, H. C. (2024). BAX and DDB2 as biomarkers for acute radiation exposure in the human blood ex vivo and non-human primate models. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-69852-z
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Wang, E., Shuryak, I., & Brenner, D. J. (2024). A competing risks machine learning study of neutron dose, fractionation, age, and sex effects on mortality in 21,000 mice. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-68717-9
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Pannkuk, E. L., Laiakis, E. C., Garty, G., Bansal, S., Jayatilake, M. M., Tan, Y., Ponnaiya, B., Wu, X., Amundson, S. A., Brenner, D. J., & Fornace, A. J. (2024). Impact of Partial Body Shielding from Very High Dose Rates on Untargeted Metabolomics in Biodosimetry. ACS Omega, 9(32), 35182–35196. https://doi.org/10.1021/acsomega.4c05688
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Columbia Affiliation
Pannkuk, E. L., Shuryak, I., Kot, A., Yun-Tien Lin, L., Li, H.-H., & Fornace, A. J. (2024). Host microbiome depletion attenuates biofluid metabolite responses following radiation exposure. PLOS ONE, 19(5), e0300883. https://doi.org/10.1371/journal.pone.0300883
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Nemzow, L., Boehringer, T., Mayenburg, J., Beaton-Green, L. A., Wilkins, R. C., & Turner, H. C. (2024). Interlaboratory comparison of high-throughput protein biomarker assay quantifications for radiation exposure classification. PLOS ONE, 19(4), e0301418. https://doi.org/10.1371/journal.pone.0301418
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Carswell, L., Sridharan, D. M., Chien, L.-C., Hirose, W., Giroux, V., Nakagawa, H., & Pluth, J. M. (2024). Modeling Radiation-Induced Epithelial Cell Injury in Murine Three-Dimensional Esophageal Organoids. Biomolecules, 14(5), 519. https://doi.org/10.3390/biom14050519
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Beaton-Green, L. A., Mayenburg, J. M., Marro, L., Hassan, E. M., Cuadros Sanchez, S., Darwish, R., Lachapelle, S., Adam, N., Burtt, J. J., Van Den Hanenberg, C., Rodrigues, M. A., Wang, Q., Brenner, D. J., Turner, H. C., & Wilkins, R. C. (2023). Application of the Cytokinesis-Block Micronucleus Assay for High-Dose Exposures Using Imaging Flow Cytometry. Cytogenetic and Genome Research, 163(3–4), 131–142. Portico. https://doi.org/10.1159/000532124
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Kanagaraj, K., Phillippi, M. A., Narayan, P., Szolc, B., Perrier, J. R., McLane, A., Wolden, S. L., Barker, C. A., Wang, Q., Amundson, S. A., Brenner, D. J., & Turner, H. C. (2023). Assessment of Micronuclei Frequency in the Peripheral Blood of Adult and Pediatric Patients Receiving Fractionated Total Body Irradiation. Cytogenetic and Genome Research, 163(3–4), 121–130. Portico. https://doi.org/10.1159/000534433
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Chen, F., Tang, C., Yang, F., Ekpenyong, A., Qin, R., Xie, J., Momen-Heravi, F., Saba, N. F., & Teng, Y. (2024). HSP90 inhibition suppresses tumor glycolytic flux to potentiate the therapeutic efficacy of radiotherapy for head and neck cancer. Science Advances, 10(8). https://doi.org/10.1126/sciadv.adk3663
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Wang, L., Rivas, R., Wilson, A., Park, Y. M., Walls, S., Yu, T., & Miller, A. C. (2023). Dose-Dependent Effects of Radiation on Mitochondrial Morphology and Clonogenic Cell Survival in Human Microvascular Endothelial Cells. Cells, 13(1), 39. https://doi.org/10.3390/cells13010039
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Wang, E., Shuryak, I., & Brenner, D. J. (2023). Quantifying the effects of neutron dose, dose protraction, age and sex on mouse survival using parametric regression and machine learning on a 21,000-mouse data set. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-49262-3
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Ghandhi, S. A., Morton, S. R., Shuryak, I., Lee, Y., Soni, R. K., Perrier, J. R., Bakke, J., Gahagan, J., Bujold, K., Authier, S., Amundson, S. A., Brenner, D. J., Nishita, D., Chang, P., & Turner, H. C. (2023). Longitudinal multi-omic changes in the transcriptome and proteome of peripheral blood cells after a 4 Gy total body radiation dose to Rhesus macaques. BMC Genomics, 24(1). https://doi.org/10.1186/s12864-023-09230-7
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Shuryak, I., Nemzow, L., Bacon, B. A., Taveras, M., Wu, X., Deoli, N., Ponnaiya, B., Garty, G., Brenner, D. J., & Turner, H. C. (2023). Machine learning approach for quantitative biodosimetry of partial-body or total-body radiation exposures by combining radiation-responsive biomarkers. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-28130-0
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Shuryak, I., Ghandhi, S. A., Laiakis, E. C., Garty, G., Wu, X., Ponnaiya, B., Kosowski, E., Pannkuk, E., Kaur, S. P., Harken, A. D., Deoli, N., Fornace, A. J., Brenner, D. J., & Amundson, S. A. (2023). Biomarker integration for improved biodosimetry of mixed neutron + photon exposures. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-37906-3
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Nemzow, L., Boehringer, T., Bacon, B., & Turner, H. C. (2023). Development of a human peripheral blood ex vivo model for rapid protein biomarker detection and applications to radiation biodosimetry. PLOS ONE, 18(8), e0289634. https://doi.org/10.1371/journal.pone.0289634
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Columbia Affiliation
Liu, Z., Cologne, J., Amundson, S. A., & Noda, A. (2023). Candidate biomarkers and persistent transcriptional responses after low and high dose ionizing radiation at high dose rate. International Journal of Radiation Biology, 99(12), 1853–1864. https://doi.org/10.1080/09553002.2023.2241897
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Columbia Affiliation
Heidarian, M., Jensen, I. J., Kannan, S. K., Pewe, L. L., Hassert, M., Park, S., Xue, H.-H., Harty, J. T., & Badovinac, V. P. (2023). Sublethal whole-body irradiation induces permanent loss and dysfunction in pathogen-specific circulating memory CD8 T cell populations. Proceedings of the National Academy of Sciences, 120(27). https://doi.org/10.1073/pnas.2302785120
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Ghandhi, S. A., Shuryak, I., Ponnaiya, B., Wu, X., Garty, G., Morton, S. R., Kaur, S. P., & Amundson, S. A. (2022). Cross-platform validation of a mouse blood gene signature for quantitative reconstruction of radiation dose. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-18558-1
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Shuryak, I., Slaba, T. C., Plante, I., Poignant, F., Blattnig, S. R., & Brenner, D. J. (2022). A practical approach for continuous in situ characterization of radiation quality factors in space. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-04937-1
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Pannkuk, E. L., Laiakis, E. C., Garty, G., Bansal, S., Ponnaiya, B., Wu, X., Ghandhi, S. A., Amundson, S. A., Brenner, D. J., & Fornace, A. J. (2022). Biofluid Metabolomics and Lipidomics of Mice Exposed to External Very High-Dose Rate Radiation. Metabolites, 12(6), 520. https://doi.org/10.3390/metabo12060520
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Columbia Affiliation
Shuryak, I., Sachs, R. K., & Brenner, D. J. (2021). Quantitative modeling of carcinogenesis induced by single beams or mixtures of space radiations using targeted and non-targeted effects. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-02883-y
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