Epidermal-Derived Hedgehog Signaling Drives Mesenchymal Proliferation during Digit Tip Regeneration

Maan, Z. N., Rinkevich, Y., Barrera, J., Chen, K., Henn, D., Foster, D., Bonham, C. A., Padmanabhan, J., Sivaraj, D., Duscher, D., Hu, M., Yan, K., Januszyk, M., Longaker, M. T., Weissman, I. L., & Gurtner, G. C. (2021). Epidermal-Derived Hedgehog Signaling Drives Mesenchymal Proliferation during Digit Tip Regeneration. Journal of Clinical Medicine, 10(18), 4261. https://doi.org/10.3390/jcm10184261

Authors:

Zeshaan N Maan

Yuval Rinkevich

Janos Barrera

Kellen Chen

Dominic Henn

Deshka Foster

Clark Andrew Bonham

Jagannath Padmanabhan

Dharshan Sivaraj

Dominik Duscher

Michael Hu

Kelley Yan

Michael Januszyk

Michael T Longaker

Irving L Weissman

Geoffrey C Gurtner

Affiliated Authors:

Kelley Yan

Columbia Affiliation:

Vagelos College of Physicians and Surgeons
- Department of Medicine
  Division of Digestive and Liver Diseases
- Department of Genetics and Development

Subjects:

Congenital limb and hand anomalies (OpenAlex Topic)

Microsurgical Reconstruction Techniques (OpenAlex Topic)

Notch Signaling Pathway in Development and Disease (OpenAlex Topic)

Author Keywords:

digit tip

regeneration

hedgehog signaling

sonic hedgehog

wnt

rainbow mouse

epimorphic regeneration

clonal proliferation

germ layer

Publication Type:

Article

Unique ID:

10.3390/jcm10184261

PMID:

DOI:

10.3390/jcm10184261

Journal:

Journal of Clinical Medicine

Publication Date:

2021-09-29

Data Source:

PubMed

Source Link:

View PubMed Record

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View Web of Science Record

View OpenAlex Record

Record Created:

Tuesday, June 10, 2025 - 10:42