Indigenous gut microbiota constitutively drive release of ciliary neurotrophic factor from mucosal enteric glia to maintain the homeostasis of enteric neural circuits

Kato, R., Yamamoto, T., Ogata, H., Miyata, K., Hayashi, S., Gershon, M. D., & Kadowaki, M. (2024). Indigenous gut microbiota constitutively drive release of ciliary neurotrophic factor from mucosal enteric glia to maintain the homeostasis of enteric neural circuits. Frontiers in Immunology, 15. https://doi.org/10.3389/fimmu.2024.1372670
Authors:
Ryo Kato
Takeshi Yamamoto
Hanako Ogata
Kana Miyata
Shusaku Hayashi
Michael D Gershon
Makoto Kadowaki
Affiliated Authors:
Michael D Gershon
Columbia Affiliation:
Subjects:
Gastrointestinal Microbiome (MeSH)
Homeostasis (MeSH)
Enteric Nervous System (MeSH)
Neuroglia (MeSH)
Ciliary Neurotrophic Factor (MeSH)
Dysbiosis (MeSH)
Mice, Inbred C57BL (MeSH)
Intestinal Mucosa (MeSH)
Author Keywords:
enteric glia
enteric nervous system
ciliary neurotrophic factor (cntf)
gut microbiota
tlr4 (toll-like receptor 4)
antibiotics
lps (lipopolysaccharide)
mucosa
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Publication Type:
Article
Unique ID:
10.3389/fimmu.2024.1372670
PMID:
39606241
DOI:
10.3389/fimmu.2024.1372670
Journal:
Frontiers in Immunology
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Web of Science Record

Record Created: