Destabilized 3’UTR elements therapeutically degrade ERBB2 mRNA in drug-resistant ERBB2+ cancer models

Awah, C. U., Glemaud, Y., Levine, F., Yang, K., Ansary, A., Dong, F., Ash, L., Zhang, J., & Ogunwobi, O. O. (2023). Destabilized 3’UTR elements therapeutically degrade ERBB2 mRNA in drug-resistant ERBB2+ cancer models. Frontiers in Genetics, 14. https://doi.org/10.3389/fgene.2023.1184600
Authors:
Chidiebere U. Awah
Yana Glemaud
Fayola Levine
Kiseok Yang
Afrin Ansary
Fu Dong
Leonard Ash
Junfei Zhang
Olorunseun O. Ogunwobi
Affiliated Authors:
Junfei Zhang
Subjects:
Regulation of Chromatin Structure and Function (OpenAlex Topic)
Genomic Landscape of Cancer and Mutational Signatures (OpenAlex Topic)
The p53 Signaling Network in Cancer Research (OpenAlex Topic)
Author Keywords:
3'utr elements
erbb2 (her2/neu)
cancer
cancer treatment
drug resistance
mrna overwriting
mrna stabilizing
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Publication Type:
Article
Unique ID:
10.3389/fgene.2023.1184600
PMID:
37359373
DOI:
10.3389/fgene.2023.1184600
Journal:
Frontiers in Genetics
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
View PubMed Record

Record Created: