A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A

Simon, M., Yang, J., Gigas, J., Earley, E. J., Hillpot, E., Zhang, L., Zagorulya, M., Tombline, G., Gilbert, M., Yuen, S. L., Pope, A., Van Meter, M., Emmrich, S., Firsanov, D., Athreya, A., Biashad, S. A., Han, J., Ryu, S., Tare, A., … Gorbunova, V. (2022). A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A. The EMBO Journal, 41(21). Portico. https://doi.org/10.15252/embj.2021110393
Authors:
Matthew Simon
Jiping Yang
Jonathan Gigas
Eric J Earley
Eric Hillpot
Lei Zhang
Maria Zagorulya
Greg Tombline
Michael Gilbert
Samantha L Yuen
Alexis Pope
Michael Van Meter
Stephan Emmrich
Denis Firsanov
Advait Athreya
Seyed Ali Biashad
Jeehae Han
Seungjin Ryu
Archana Tare
Yizhou Zhu
Adam Hudgins
Gil Atzmon
Nir Barzilai
Aaron Wolfe
Kelsey Moody
Benjamin A Garcia
David D Thomas
Paul D Robbins
Jan Vijg
Andrei Seluanov
Yousin Suh
Vera Gorbunova
Affiliated Authors:
Jiping Yang
Alexis Pope
Yousin Suh
Columbia Affiliation:
Subjects:
Lamin Type A (MeSH)
Sirtuins (MeSH)
Author Keywords:
sirt6
centenarians
lamin
longevity
elink
Publication Type:
Article
Unique ID:
10.15252/embj.2021110393
PMID:
36215696
DOI:
10.15252/embj.2021110393
Journal:
EMBO Journal
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

Record Created: