Reduction of Glut1 in the Neural Retina But Not the RPE Alleviates Polyol Accumulation and Normalizes Early Characteristics of Diabetic Retinopathy

Holoman, N. C., Aiello, J. J., Trobenter, T. D., Tarchick, M. J., Kozlowski, M. R., Makowski, E. R., De Vivo, D. C., Singh, C., Sears, J. E., & Samuels, I. S. (2021). Reduction of Glut1 in the Neural Retina But Not the RPE Alleviates Polyol Accumulation and Normalizes Early Characteristics of Diabetic Retinopathy. The Journal of Neuroscience, 41(14), 3275–3299. https://doi.org/10.1523/jneurosci.2010-20.2021
Authors:
Nicholas C. Holoman
Jacob J. Aiello
Timothy D. Trobenter
Matthew J. Tarchick
Michael R. Kozlowski
Emily R. Makowski
Ivy S. Samuels
Charandeep Singh
Jonathan E. Sears
Darryl C. De Vivo
Affiliated Authors:
Darryl C. De Vivo
Author Keywords:
diabetic retinopathy
electroretinogram
glucose
photoreceptor
retinal pigment epithelium
sorbitol
Grants:
R01EY024972 (NIH – National Eye Institute)
P30EY025585 (NIH – National Eye Institute)
I01BX002754 (NIH – Veterans Affairs)
Publication Type:
Article
Unique ID:
10.1523/JNEUROSCI.2010-20.2021
PMID:
Publication Date:
Data Source:
Web of Science

Record Created: