Irradiation-responsive PRDM10-DT modulates the angiogenic response in human NSCLC cells in an SP1-dependent manner via the miR-663a/TGF-β1 axis

Huang, H., Xu, Y., Guo, Z., Zhang, M., Li, W., Song, Y., Nie, J., Hu, W., Hei, T. K., & Zhou, G. (2025). Irradiation-responsive PRDM10-DT modulates the angiogenic response in human NSCLC cells in an SP1-dependent manner via the miR-663a/TGF-β1 axis. Journal of Translational Medicine, 23(1). https://doi.org/10.1186/s12967-025-06273-0
Authors:
Hao Huang
Ying Xu
Zi Guo
Miaomiao Zhang
Wanshi Li
Yidan Song
Jing Nie
Wentao Hu
Tom K Hei
Guangming Zhou
Affiliated Authors:
Tom K Hei
Columbia Affiliation:
Subjects:
Sp1 Transcription Factor (MeSH)
MicroRNAs (MeSH)
Transforming Growth Factor beta1 (MeSH)
Carcinoma, Non-Small-Cell Lung (MeSH)
Lung Neoplasms (MeSH)
Neovascularization, Pathologic (MeSH)
Transcription Factors (MeSH)
Author Keywords:
angiogenesis
carbon ion
prdm10-dt
sp1
tgf-β1
x-ray
elink
Publication Type:
Article
Unique ID:
10.1186/s12967-025-06273-0
PMID:
40016776
DOI:
10.1186/s12967-025-06273-0
Journal:
Journal of Translational Medicine
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

Record Created: