Loss of GalNAc-T14 links O-glycosylation defects to alterations in B cell homing in IgA nephropathy

Prakash, S., Steers, N. J., Li, Y., Sanchez-Rodriguez, E., Verbitsky, M., Robbins, I., Simpson, J., Pathak, S., Raska, M., Reily, C., Ng, A., Liang, J., DeMaria, N., Katiraei, A., Stevens, K. O., Fischman, C., Shapiro, S., Kodali, S., McCutchan, J., … Gharavi, A. G. (2025). Loss of GalNAc-T14 links O-glycosylation defects to alterations in B cell homing in IgA nephropathy. Journal of Clinical Investigation, 135(10). https://doi.org/10.1172/jci181164
Authors:
Sindhuri Prakash
Nicholas J. Steers
Yifu Li
Elena Sanchez-Rodriguez
Miguel Verbitsky
Isabel Robbins
Jenna Simpson
Sharvari Pathak
Milan Raska
Colin Reily
Anna Ng
Judy Liang
Natalia DeMaria
Amanda Katiraei
Kelsey O. Stevens
Clara Fischman
Samantha Shapiro
Swetha Kodali
Jason McCutchan
Heekuk Park
Djamila Eliby
Marco Delsante
Landino Allegri
Enrico Fiaccadori
Monica Bodria
Maddalena Marasa
Elizabeth Raveche
Bruce A. Julian
Anne-Catrin Uhlemann
Krzysztof Kiryluk
Hong Zhang
Vivette D. D’Agati
Simone Sanna-Cherchi
Jan Novak
Ali G. Gharavi
Affiliated Authors:
Sindhuri Prakash
Nicholas J. Steers
Yifu Li
Elena Sanchez-Rodriguez
Miguel Verbitsky
Isabel Robbins
Jenna Simpson
Sharvari Pathak
Anna Ng
Judy Liang
Natalia DeMaria
Amanda Katiraei
Kelsey O. Stevens
Clara Fischman
Samantha Shapiro
Swetha Kodali
Jason McCutchan
Heekuk Park
Djamila Eliby
Monica Bodria
Maddalena Marasa
Anne-Catrin Uhlemann
Krzysztof Kiryluk
Vivette D. D’Agati
Simone Sanna-Cherchi
Ali G. Gharavi
Columbia Affiliation:
Subjects:
Glomerulonephritis, IGA (MeSH)
N-Acetylgalactosaminyltransferases (MeSH)
B-Lymphocytes (MeSH)
Author Keywords:
genetic diseases
genetics
glycobiology
immunoglobulins
nephrology
elink
Publication Type:
Article
Unique ID:
10.1172/JCI181164
PMID:
40153534
DOI:
10.1172/JCI181164
Journal:
Journal of Clinical Investigation
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View PubMed Record

Record Created: