An in vivo screen identifies diverse domains that can act as force-dependent proteolytic switches for Notch activation

Baker, F. C., Harman, J., Jordan, T., Walton, B., Ajamu-Johnson, A., Alashqar, R. F., Bhikot, S., Struhl, G., & Langridge, P. D. (2025). An in vivo screen identifies diverse domains that can act as force-dependent proteolytic switches for Notch activation. Science Signaling, 18(890). https://doi.org/10.1126/scisignal.adt4606

Authors:

Frederick C Baker

Jacob Harman

Trevor Jordan

Breana Walton

Amber Ajamu-Johnson

Rama F Alashqar

Simran Bhikot

Gary Struhl

Paul D Langridge

Affiliated Authors:

Gary Struhl