Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127

Montoya, S., Bourcier, J., Noviski, M., Lu, H., Thompson, M. C., Chirino, A., Jahn, J., Sondhi, A. K., Gajewski, S., Tan, Y. S. (May), Yung, S., Urban, A., Wang, E., Han, C., Mi, X., Kim, W. J., Sievers, Q., Auger, P., Bousquet, H., … Taylor, J. (2024). Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127. Science, 383(6682). https://doi.org/10.1126/science.adi5798
Authors:
Skye Montoya
Alexandra Chirino
Jacob Jahn
Anya K. Sondhi
Carla Barrientos Risso
Daniel Tsai
Gabriel Pardo
Alejandro Pardo
Maurizio Affer
Vindhya Nawaratne
Tulasigeri M. Totiger
Alvaro Alencar
Justin Taylor
Jessie Bourcier
Xiaoli Mi
Won Jun Kim
Quinlan Sievers
Camila Pena-Velasquez
Lindsey E. Roeker
Sigrid S. Skanland
Anthony R. Mato
Omar Abdel-Wahab
Mark Noviski
Hao Lu
Stefan Gajewski
Ying Siow (May) Tan
Stephanie Yung
Paul Auger
Hugo Bousquet
Nivetha Brathaban
Brandon Bravo
Melissa Gessner
Cristiana Guiducci
James N. Iuliano
Tim Kane
Ratul Mukerji
Panga Jaipal Reddy
Janine Powers
Mateo Sanchez Garcia de los Rios
Jordan Ye
Robert J. Brown
Gwenn M. Hansen
Meghan C. Thompson
Aleksandra Urban
Eric Wang
Cuijuan Han
Ryan Q. Notti
Joanna M. Rhodes
Andrew D. Zelenetz
Sanjoy Mehta
Ralph Garippa
Adam Linley
Rajesh Kumar Soni
Affiliated Authors:
Rajesh Kumar Soni
Columbia Affiliation:
elink
Publication Type:
Article
Unique ID:
10.1126/science.adi5798
PMID:
38301010
DOI:
10.1126/science.adi5798
Journal:
Science
Publication Date:
Data Source:
Web of Science
Source Link:
View Web of Science Record

Record Created: