A Randomized Double-Blinded Placebo Controlled Trial of Clazakizumab for the Treatment of COVID-19 Pneumonia With Hyperinflammation

Lonze, B. E., Spiegler, P., Wesson, R. N., Alachkar, N., Petkova, E., Weldon, E. P., Dieter, R. A., Li, Y., Quinn, M., Mattoo, A., Soomro, I., Cohen, S. M., Leung, S., Deterville, C. L., Landrum, B. M., Ali, M. I., Cohen, D. J., Singer, A. L., Sen, A., … Montgomery, R. A. (2022). A Randomized Double-Blinded Placebo Controlled Trial of Clazakizumab for the Treatment of COVID-19 Pneumonia With Hyperinflammation*. Critical Care Medicine, 50(9), 1348–1359. https://doi.org/10.1097/ccm.0000000000005591
Authors:
Bonnie E Lonze
Peter Spiegler
Russell N Wesson
Nada Alachkar
Eva Petkova
Elaina P Weldon
Rebecca A Dieter
Yi Li
Max Quinn
Aprajita Mattoo
Irfana Soomro
Steven M Cohen
Sherry Leung
Cecilia L Deterville
B Mark Landrum
Muhammad Imran Ali
David J Cohen
Andrew L Singer
Ayan Sen
Edward Chong
Judith S Hochman
Andrea B Troxel
Robert A Montgomery
Affiliated Authors:
David J Cohen
Columbia Affiliation:
Subjects:
Coronavirus Disease 2019 (OpenAlex Topic)
Coronavirus Disease 2019 Research (OpenAlex Topic)
Neurological Manifestations of COVID-19 Infection (OpenAlex Topic)
Antibodies, Monoclonal, Humanized (MeSH)
COVID-19 (MeSH)
COVID-19 Drug Treatment (MeSH)
Author Keywords:
acute respiratory distress syndrome
clazakizumab
covid-19
cytokine inhibition
hyperinflammation
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Publication Type:
Article
Unique ID:
10.1097/ccm.0000000000005591
PMID:
35583232
DOI:
10.1097/ccm.0000000000005591
Journal:
Critical Care Medicine
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created: