Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency

Das, A., Sudhaman, S., Morgenstern, D., Coblentz, A., Chung, J., Stone, S. C., Alsafwani, N., Liu, Z. A., Karsaneh, O. A. A., Soleimani, S., Ladany, H., Chen, D., Zatzman, M., Cabric, V., Nobre, L., Bianchi, V., Edwards, M., Sambira Nahum, L. C., Ercan, A. B., … Tabori, U. (2022). Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency. Nature Medicine, 28(1), 125–135. https://doi.org/10.1038/s41591-021-01581-6
Authors:
Anirban Das
Sumedha Sudhaman
Daniel Morgenstern
Ailish Coblentz
Jiil Chung
Simone C Stone
Noor Alsafwani
Zhihui Amy Liu
Ola Abu Al Karsaneh
Shirin Soleimani
Hagay Ladany
David Chen
Matthew Zatzman
Vanja Cabric
Liana Nobre
Vanessa Bianchi
Melissa Edwards
Lauren C Sambira Nahum
Ayse B Ercan
Arash Nabbi
Shlomi Constantini
Rina Dvir
Michal Yalon-Oren
Gadi Abebe Campino
Shani Caspi
Valerie Larouche
Alyssa Reddy
Michael Osborn
Gary Mason
Scott Lindhorst
Annika Bronsema
Vanan Magimairajan
Enrico Opocher
Rebecca Loret De Mola
Magnus Sabel
Charlotta Frojd
David Sumerauer
David Samuel
Kristina Cole
Stefano Chiaravalli
Maura Massimino
Patrick Tomboc
David S Ziegler
Ben George
An Van Damme
Nobuko Hijiya
David Gass
Rose B McGee
Oz Mordechai
Daniel C Bowers
Theodore W Laetsch
Alexander Lossos
Deborah T Blumenthal
Tomasz Sarosiek
Lee Yi Yen
Jeffrey Knipstein
Anne Bendel
Lindsey M Hoffman
Sandra Luna-Fineman
Stefanie Zimmermann
Isabelle Scheers
Kim E Nichols
Michal Zapotocky
Jordan R Hansford
John M Maris
Peter Dirks
Michael D Taylor
Abhaya V Kulkarni
Manohar Shroff
Derek S Tsang
Anita Villani
Wei Xu
Melyssa Aronson
Carol Durno
Adam Shlien
David Malkin
Gad Getz
Yosef E Maruvka
Pamela S Ohashi
Cynthia Hawkins
Trevor J Pugh
Eric Bouffet
Uri Tabori
Affiliated Authors:
Nobuko Hijiya
Columbia Affiliation:
Subjects:
Molecular Characterization of Colorectal Cancer (OpenAlex Topic)
Genomic Landscape of Cancer and Mutational Signatures (OpenAlex Topic)
Cancer Immunotherapy (OpenAlex Topic)
B7-H1 Antigen (MeSH)
DNA Repair (MeSH)
DNA Replication (MeSH)
Germ-Line Mutation (MeSH)
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Publication Type:
Article
Unique ID:
10.1038/s41591-021-01581-6
PMID:
34992263
DOI:
10.1038/s41591-021-01581-6
Journal:
Nature Medicine
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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View Web of Science Record

Record Created: