Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum

Lee, D. S. M., Cardone, K. M., Zhang, D. Y., Tsao, N. L., Abramowitz, S., Sharma, P., DePaolo, J. S., Conery, M., Aragam, K. G., Biddinger, K., Dilitikas, O., Hoffman-Andrews, L., Judy, R. L., Khan, A., Kullo, I. J., Puckelwartz, M. J., Reza, N., Satterfield, B. A., Singhal, P., … Damrauer, S. M. (2025). Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum. Nature Genetics, 57(4), 829–838. https://doi.org/10.1038/s41588-025-02140-2
Authors:
David S M Lee
Kathleen M Cardone
David Y Zhang
Noah L Tsao
Sarah Abramowitz
Pranav Sharma
John S DePaolo
Mitchell Conery
Krishna G Aragam
Kiran Biddinger
Ozan Dilitikas
Lily Hoffman-Andrews
Renae L Judy
Atlas Khan
Iftikhar J Kullo
Megan J Puckelwartz
Nosheen Reza
Benjamin A Satterfield
Pankhuri Singhal
Zoltan Arany
Thomas P Cappola
Eric D Carruth
Sharlene M Day
Ron Do
Christopher M Haggerty
Jacob Joseph
Elizabeth M McNally
Girish Nadkarni
Anjali T Owens
Daniel J Rader
Marylyn D Ritchie
Yan V Sun
Benjamin F Voight
Michael G Levin
Scott M Damrauer
Affiliated Authors:
Atlas Khan
Columbia Affiliation:
Subjects:
Heart Failure (MeSH)
Genetic Predisposition to Disease (MeSH)
Gene Frequency (MeSH)
Genetic Variation (MeSH)
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Publication Type:
Article
Unique ID:
10.1038/s41588-025-02140-2
PMID:
40195560
DOI:
10.1038/s41588-025-02140-2
Journal:
Nature Genetics
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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