Chronic arsenic exposure of ovarian surface and fallopian tube cultures induces giant and/or multinucleated cells with phagocytosis-like properties and an inflammatory phenotype

Andrade-Feraud, C. M., Acanda de la Rocha, A. M., Berlow, N. E., Duque, S., Velazco, A., Castillo, D., Holcomb, B., Coats, E. R., Ghurani, Y. R., Lucey, C. M., Pearson, B., Guilarte, T. R., & Azzam, D. J. (2025). Chronic arsenic exposure of ovarian surface and fallopian tube cultures induces giant and/or multinucleated cells with phagocytosis-like properties and an inflammatory phenotype. Toxicology and Applied Pharmacology, 500, 117394. https://doi.org/10.1016/j.taap.2025.117394
Authors:
Cristina M Andrade-Feraud
Arlet M Acanda de la Rocha
Noah E Berlow
Santiago Duque
Alexander Velazco
Diego Castillo
Baylee Holcomb
Ebony R Coats
Yasmin R Ghurani
Catherine M Lucey
Brandon Pearson
Tomás R Guilarte
Diana J Azzam
Affiliated Authors:
Catherine M Lucey
Subjects:
Phagocytosis (MeSH)
Ovary (MeSH)
Arsenic (MeSH)
Giant Cells (MeSH)
Inflammation (MeSH)
Author Keywords:
arsenic
carcinogenesis
chronic exposure
chronic inflammation
dna damage
giant cells
human primary cultures
multinucleated cells
nf-kb pathway
ovary
Publication Type:
Article
Unique ID:
10.1016/j.taap.2025.117394
PMID:
Publication Date:
Data Source:
PubMed

Record Created: