Selective removal of astrocytic PERK protects against glymphatic impairment and decreases toxic aggregation of β-amyloid and tau

Chen, K., Morizawa, Y. M., Nuriel, T., Al-Dalahmah, O., Xie, Z., & Yang, G. (2025). Selective removal of astrocytic PERK protects against glymphatic impairment and decreases toxic aggregation of β-amyloid and tau. Neuron. https://doi.org/10.1016/j.neuron.2025.04.027
Authors:
Kai Chen
Yosuke M Morizawa
Tal Nuriel
Osama Al-Dalahmah
Zhongcong Xie
Guang Yang
Affiliated Authors:
Kai Chen
Yosuke M Morizawa
Tal Nuriel
Osama Al-Dalahmah
Guang Yang
Columbia Affiliation:
Author Keywords:
ad
aqp4
ck2
perk
astrocyte
glymphatic function
protein synthesis
unfolded protein response
elink
Publication Type:
Article
Unique ID:
10.1016/j.neuron.2025.04.027
PMID:
40403715
DOI:
10.1016/j.neuron.2025.04.027
Journal:
Neuron
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

Record Created: