Lactate is an epigenetic metabolite that drives survival in model systems of glioblastoma

Torrini, C., Nguyen, T. T. T., Shu, C., Mela, A., Humala, N., Mahajan, A., Seeley, E. H., Zhang, G., Westhoff, M.-A., Karpel-Massler, G., Bruce, J. N., Canoll, P., & Siegelin, M. D. (2022). Lactate is an epigenetic metabolite that drives survival in model systems of glioblastoma. Molecular Cell, 82(16), 3061-3076.e6. https://doi.org/10.1016/j.molcel.2022.06.030

Authors:

Consuelo Torrini

Trang Nguyen

Chang Shu

Angeliki Mela

Nelson Humala

Aayushi Mahajan

Erin Heather Seeley

Guoan Zhang

Mike‐Andrew Westhoff

Georg Karpel‐Massler

Jeffrey N. Bruce

Peter Canoll

Markus D. Siegelin

Affiliated Authors:

Consuelo Torrini

Trang Nguyen

Chang Shu

Angeliki Mela

Nelson Humala

Aayushi Mahajan

Jeffrey N. Bruce

Peter Canoll

Markus D. Siegelin

Columbia Affiliation:

Vagelos College of Physicians and Surgeons
- Department of Pathology and Cell Biology
- Department of Neurosurgery

Subjects:

Glioblastoma (MeSH)

Gliomas (OpenAlex Topic)

Metabolic Reprogramming in Cancer Biology (OpenAlex Topic)

Epigenetic Modifications and Their Functional Implications (OpenAlex Topic)

Author Keywords:

atac-seq

chip-seq

glioblastoma

lactate

metabolic flux analysis

tumor metabolism

Publication Type:

Article

Unique ID:

10.1016/j.molcel.2022.06.030

PMID:

DOI:

10.1016/j.molcel.2022.06.030

Journal:

Publication Date:

2022-08-01

Data Source:

OpenAlex

Source Link:

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Record Created:

Thursday, December 12, 2024 - 15:23