Development of high-affinity nanobodies specific for NaV1.4 and NaV1.5 voltage-gated sodium channel isoforms

Srinivasan, L., Alzogaray, V., Selvakumar, D., Nathan, S., Yoder, J. B., Wright, K. M., Klinke, S., Nwafor, J. N., Labanda, M. S., Goldbaum, F. A., Schön, A., Freire, E., Tomaselli, G. F., Amzel, L. M., Ben-Johny, M., & Gabelli, S. B. (2022). Development of high-affinity nanobodies specific for NaV1.4 and NaV1.5 voltage-gated sodium channel isoforms. Journal of Biological Chemistry, 298(4), 101763. https://doi.org/10.1016/j.jbc.2022.101763
Authors:
Lakshmi Srinivasan
Sara Nathan
Jesse B. Yoder
Katharine M. Wright
Justin N. Nwafor
L. Mario Amzel
Sandra B. Gabelli
Vanina Alzogaray
Sebastian Klinke
Maria S. Labanda
Fernando A. Goldbaum
Dakshnamurthy Selvakumar
Arne Schon
Ernesto Freire
Gordon F. Tomaselli
Manu Ben-Johny
Affiliated Authors:
Manu Ben-Johny
Columbia Affiliation:
Subjects:
Single-Domain Antibodies (MeSH)
Voltage-Gated Sodium Channels (MeSH)
Author Keywords:
fret
lama glama
na(v)1.4
na(v)1.5
x-ray diffraction
biolayer interferometry
hipsc-cm
nanobody
voltage-gated sodium channel
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Publication Type:
Article
Unique ID:
10.1016/j.jbc.2022.101763
PMID:
35202650
DOI:
10.1016/j.jbc.2022.101763
Journal:
Journal of Biological Chemistry
Publication Date:
Data Source:
Web of Science
Source Link:
View Web of Science Record
View PubMed Record

Record Created: