Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection

Wong Fok Lung, T., Charytonowicz, D., Beaumont, K. G., Shah, S. S., Sridhar, S. H., Gorrie, C. L., Mu, A., Hofstaedter, C. E., Varisco, D., McConville, T. H., Drikic, M., Fowler, B., Urso, A., Shi, W., Fucich, D., Annavajhala, M. K., Khan, I. N., Oussenko, I., Francoeur, N., … Prince, A. (2022). Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection. Cell Metabolism, 34(5), 761-774.e9. https://doi.org/10.1016/j.cmet.2022.03.009
Authors:
Tania Wong Fok Lung
Daniel Charytonowicz
Kristin G. Beaumont
Shivang S. Shah
Shwetha H. Sridhar
Claire L. Gorrie
Andre Mu
Casey E. Hofstaedter
David Varisco
Thomas H. McConville
Marija Drikic
Brandon Fowler
Andreacarola Urso
Wei Shi
Dario Fucich
Medini K. Annavajhala
Ibrahim N. Khan
Irina Oussenko
Nancy Francoeur
Melissa L. Smith
Brent R. Stockwell
Ian A. Lewis
Abderrahman Hachani
Swikrity Upadhyay Baskota
Anne-Catrin Uhlemann
Danielle Ahn
Robert K. Ernst
Benjamin P. Howden
Robert Sebra
Alice Prince
Affiliated Authors:
Tania Wong Fok Lung
Shivang S. Shah
Thomas H. McConville
Brandon Fowler
Andreacarola Urso
Wei Shi
Dario Fucich
Medini K. Annavajhala
Ibrahim N. Khan
Brent R. Stockwell
Swikrity Upadhyay Baskota
Anne-Catrin Uhlemann
Danielle Ahn
Alice Prince
Columbia Affiliation:
Subjects:
Klebsiella Infections (MeSH)
Klebsiella pneumoniae (MeSH)
Author Keywords:
klebsiella pneumoniae
m2 macrophages
mdscs
bacterial adaptation
disease tolerance
immunometabolism
immunosuppression
itaconate
pulmonary infection
type 6 secretion system
elink
Publication Type:
Article
Unique ID:
10.1016/j.cmet.2022.03.009
PMID:
35413274
DOI:
10.1016/j.cmet.2022.03.009
Journal:
Cell Metabolism
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
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Record Created: