Defining the cellular origin of seminoma by transcriptional and epigenetic mapping to the normal human germline

Cheng, K., Seita, Y., Whelan, E. C., Yokomizo, R., Hwang, Y. S., Rotolo, A., Krantz, I. D., Ginsberg, J. P., Kolon, T. F., Lal, P., Luo, X., Pierorazio, P. M., Linn, R. L., Ryeom, S., & Sasaki, K. (2024). Defining the cellular origin of seminoma by transcriptional and epigenetic mapping to the normal human germline. Cell Reports, 43(6), 114323. https://doi.org/10.1016/j.celrep.2024.114323
Authors:
Keren Cheng
Yasunari Seita
Eoin C. Whelan
Ryo Yokomizo
Young Sun Hwang
Antonia Rotolo
Ian D. Krantz
Jill P. Ginsberg
Thomas F. Kolon
Priti Lal
Xunda Luo
Phillip M. Pierorazio
Rebecca L. Linn
Sandra Ryeom
Kotaro Sasaki
Affiliated Authors:
Sandra Ryeom
Columbia Affiliation:
Subjects:
Seminoma (MeSH)
Germ Cells (MeSH)
Epigenesis, Genetic (MeSH)
Testicular Neoplasms (MeSH)
Mechanisms and Applications of RNA Interference (OpenAlex Topic)
Testicular Germ Cell Tumors and Treatment (OpenAlex Topic)
Targeted Protein Degradation in Biomedical Research (OpenAlex Topic)
Author Keywords:
cp: cancer
cp: developmental biology
human germ cell development
human induced pluripotent stem cells
human male germ cells
isochromosome 12p
pallister-killian syndrome
primordial germ cells
prospermatogonia
seminoma
testicular germ cell tumor
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Publication Type:
Article
Unique ID:
10.1016/j.celrep.2024.114323
PMID:
38861385
DOI:
10.1016/j.celrep.2024.114323
Journal:
Cell Reports
Publication Date:
Data Source:
OpenAlex
Source Link:
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